Sort   by:  
 Page size 
ProteomicsAlterations in the Interactome of Serine/Threonine Protein Phosphatase Type-1 in Atrial Fibrillation Patients
Objectives: To test the hypothesis that serine/threonine protein phosphatase type-1 (PP1) is dysregulated in paroxysmal atrial fibrillation (pAF) at the level of its regulatory subunits (R-subunits). Background: AF is the most common sustained cardiac arrhythmia yet current pharmacologic treatment i...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2015-03-30 | PXD000697 | Pride
Human Label-free quantification Q-exactive Mouse Protein phosphatase 1 Paroxysmal atrial fibrillation Ltq-orbitrap elite 
ProteomicsA molecular model of sea urchin reversible adhesion based on quantitative proteomics
Marine bioadhesives have unmatched performances especially in wet environments, being valuable sources of inspiration for industrial and biomedical applications. In sea urchins specialized adhesive organs, called tube feet, mediate adhesion. These are composed by a disc, which produces adhesive and ...
ORGANISM(S): Paracentrotus lividus (Common sea urchin) 
2016-03-21 | PXD003122 | Pride
Sea urchin Echinoderm Tube foot adhesive protein Reversible adhesion Paracentrotus lividus Quantitative proteomics 
ProteomicsCombining deep-sequencing, proteomics, phosphoproteomics and functional screens to discover novel regulators of sphingolipids homeostasis.
Sphingolipids (SLs) are essential components of cell membranes and broad-range bioactive signaling molecules. SL levels must be tightly regulated as imbalances affect cellular function and contribute to pathologies ranging from neurodegenerative and metabolic disorders to cancer and aging. Decipheri...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-05-04 | PXD003463 | Pride
Myriocin Saccharomyces cerevisiae Sphingolipid metabolism Label-free quantification Lc-ms/ms 
OtherAlterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients.
Data from ProteomeXchange, PXD ID: PXD000697. Exiperiment: PP1_Mouse_raw_IgG, file: OR8_121211_NL_DC_PP1_Gel4_B_labelfree2.mzml. Published as part of J Am Coll Cardiol. 2015 Jan 20;65(2):163-73 . From the Abstract: {{i}} Cardiac lysates were coimmunoprecipitated with anti-PP1c antibody followed by ...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320014437 | GPMDB
Resource Reanalysis 
Sort   by:  
 Page size