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TranscriptomicsGene silencing triggers Polycomb Repressive Complex 2 recruitment to CpG islands genome-wide [iTC-seq_drugs]
Polycomb group (PcG) proteins are required for normal differentiation and development, and their activity is found deregulated in cancer. PcG proteins are involved in gene silencing, however, whether they initiate or maintain transcriptional repression is a subject of debate. Here, we show that knoc...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-58018 | biostudies-arrayexpress
GenomicsGene silencing triggers Polycomb Repressive Complex 2 recruitment to CpG islands genome-wide [ChIP-seq_Input]
Polycomb group (PcG) proteins are required for normal differentiation and development, and their activity is found deregulated in cancer. PcG proteins are involved in gene silencing, however, whether they initiate or maintain transcriptional repression is a subject of debate. Here, we show that knoc...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-58022 | biostudies-arrayexpress
GenomicsGene silencing triggers Polycomb Repressive Complex 2 recruitment to CpG islands genome-wide [ChIP-seq_drugs]
Polycomb group (PcG) proteins are required for normal differentiation and development, and their activity is found deregulated in cancer. PcG proteins are involved in gene silencing, however, whether they initiate or maintain transcriptional repression is a subject of debate. Here, we show that knoc...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-58019 | biostudies-arrayexpress
TranscriptomicsGene silencing triggers Polycomb Repressive Complex 2 recruitment to CpG islands genome-wide [RNA-seq_differentiation]
Polycomb group (PcG) proteins are required for normal differentiation and development, and their activity is found deregulated in cancer. PcG proteins are involved in gene silencing, however, whether they initiate or maintain transcriptional repression is a subject of debate. Here, we show that knoc...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-58017 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptiation to determine the genome wide distribution of PcG and TrxG proteins in Drosophila - part I
We used ChIP on chip assays to determine the genome wide distribution of a large set of PcG and trxG proteins, their associated histone marks and four candidate DNA-binding factors for PcG protein recruitment.
ORGANISM(S): Drosophila melanogaster 
2008-07-26 | E-MEXP-1708 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptiation to determine the genome wide distribution of PcG and TrxG proteins in Drosophila - part II
We used ChIP on chip assays to determine the genome wide distribution of a large set of PcG and trxG proteins, their associated histone marks and four candidate DNA-binding factors for PcG protein recruitment.
ORGANISM(S): Drosophila melanogaster 
2008-07-26 | E-MTAB-45 | biostudies-arrayexpress
TranscriptomicsChromosome conformation capture on chip (4C) at the Fab7 polycomb response element in the bithorax complex of Drosophila
In Drosophila melanogaster, Hox genes are organized in an anterior and a posterior cluster, called Antennapedia complex and bithorax complex, located on the same chromosome arm and separated by 10 Mb of DNA. Both clusters are repressed by Polycomb group (PcG) proteins. Here, we show that genes of th...
ORGANISM(S): Drosophila melanogaster 
2010-12-31 | E-GEOD-23887 | biostudies-arrayexpress
UnknownPrecision Population Medicine in Primary Care: The Sanford Chip Experience.
Not available
S-EPMC7994529 | biostudies-literature
UnknownPrioritizing Measures That Matter Within a Person-Centered Oncology Learning Health System.
Not available
S-EPMC9219163 | biostudies-literature
UnknownEffects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial.
Not available
S-EPMC10882511 | biostudies-literature
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