Soil-borne microbes can establish compatible relationships with host plants, providing a large variety of nutritive and protective compounds in exchange for photosynthesized sugars. However, the molecular mechanisms mediating the establishment of these beneficial relationships remain unclear. Our pr...
Cells use glycolytic intermediates for anabolism e.g., via the serine synthesis and pentose phosphate pathways. However, we still understand poorly how these metabolic pathways contribute to skeletal muscle cell biomass generation. The first aim of this study was therefore to identify enzymes tha...
With the aging of the population, the incidence of postmenopausal osteoporosis (PMOP) is increasing. Artemisiae Scopariae Herba (Yinchen, YC) extracts have been reported to promote osteogenic differentiation and bone formation, but the specific mechanism is ...
MASP-3 is the third protease of the lectin pathway of the complement system, but its biological function has remained obscure. To elucidate its role in complement activation, we developed a specific MASP-3 inhibitor (named TFMI-3). In this work we unambiguously demonstrate that MASP-3 acts as the ex...
