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ProteomicsEngineered allostery in a light-regulated version of TurboID for precise spatiotemporal control of proximity labeling in living cells
Lee SY, Chea JS, Zhao BX, Xu C, Udeshi ND, Roh H, Kim C, Cho K, Carr SA, Ting A. 2022 The incorporation of light-responsive domains into engineered proteins has produced optogenetic tools with the ability to regulate protein localization, interactions, and function with light. We introduced this mod...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-09 | MSV000090683 | MassIVE
TranscriptomicsTranscriptome profiling of human pre-B ALL cell line 697 upon PBX1 or TCF3 knockdown (RNA-seq)
RNA-seq was performed to observe the gene expression changes in 697 cells following shRNA-mediated knockdown of PBX Homeobox 1 (PBX1) or Transcription Factor 3 (TCF3/E2A), each with two shRNAs. Cells treated with scrambled control shRNA were used as controls.
ORGANISM(S): Homo sapiens 
2020-05-13 | E-MTAB-8179 | biostudies-arrayexpress
TranscriptomicsEpigenetic modifications and their relationships to smRNA and mRNA transcriptomes in maize
Genome-wide and organ-specific landscapes of epigenetic modifications and their relationships to mRNA and smRNA transcriptomes in maize We report an integrated genome-wide analysis of DNA methylation, histone modifications, smRNAs and mRNA transcriptional activity, using maize as a model. We surveye...
ORGANISM(S): Zea mays 
2009-04-27 | E-GEOD-15286 | biostudies-arrayexpress
UnknownMagnetic exchange interaction between unpaired π- and d-electrons in nanographene-metal coordination complexes.
Not available
S-EPMC11887856 | biostudies-literature
TranscriptomicsGenome-wide maps of Usp16, ubH2A and gene expression profiles in wild type and Usp16 knock out mouse embryonic stem cells (ESCs) and embryoid bodies (EBs)
Polycomb Repressive Complex 1 and histone H2A ubiquitination (ubH2A) contribute to embryonic stem cell (ESC) pluripotency by repressing lineage-specific gene expression. However, whether active deubiquitination co-regulates ubH2A levels in ESCs and during differentiation is not known. Here, we repor...
ORGANISM(S): Mus musculus 
2014-05-02 | E-GEOD-52899 | biostudies-arrayexpress
TranscriptomicsGene profiling within the orexin-producing neurons
Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions (cataplexy). The best biological marker of narcolepsy is orexin deficiency with dramatic loss in hypothalamic orexin-producing neurons. Together with a tight HLA and...
ORGANISM(S): Mus musculus 
2010-02-24 | E-GEOD-17617 | biostudies-arrayexpress
UnknownTransforming jet flavour tagging at ATLAS.
Not available
S-EPMC12804921 | biostudies-literature
UnknownEffect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial.
Not available
S-EPMC3668094 | biostudies-literature
UnknownDifferential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Not available
S-EPMC9192715 | biostudies-literature
UnknownDiabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019.
Not available
S-EPMC8860753 | biostudies-literature
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