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TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
TranscriptomicsThe microRNA expression profile of C2C12 cell upon 72 hours of BMP2 treatment
To identify osteoblast specific miRNAs that can contribute to osteoblastogenesis by post-transcriptionally regulates their targets, BMP2 are treated to C2C12 for 72 hours and performed miRNA microarray. C2C12 cells were treated with vehicles or BMP2 (300 ng/mL) supplemented alpha-MEM media for 72 da...
ORGANISM(S): Mus musculus 
2012-05-02 | E-GEOD-37036 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human tumor and stroma from breast catured by LCM of inflammatory and non inflammatory breast cancers
Tumor epithelium and surrounding stromal cells were isolated using laser capture microdissection of human breast cancer to examine differences in gene expression based on tissue types from inflammatory and non-inflammatory breast cancer Experiment Overall Design: We applied LCM to obtain samples enr...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5847 | biostudies-arrayexpress
TranscriptomicsCDK7-dependent Transcriptional Addiction in Triple-Negative Breast Cancer (Microarray)
Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that exhibits extremely high levels of genetic complexity and yet a relatively uniform transcriptional program. We postulate that TNBC might be highly dependent on uninterrupted transcription of a key set of genes with...
ORGANISM(S): Homo sapiens 
2015-09-24 | E-GEOD-69106 | biostudies-arrayexpress
UnknownSingle-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease.
Not available
S-EPMC8166295 | biostudies-literature
GenomicsAn Oncogenic Super-Enhancer Formed through Somatic Mutation of a Noncoding Intergenic Element
In many cancers, critical oncogenes are driven from large regulatory elements, called super-enhancers, which recruit much of the cellM-bM-^@M-^Ys transcriptional apparatus and are defined by extensive H3K27 acetylation. We found that in T-cell acute lymphoblastic leukemia (T-ALL), somatic heterozyg...
ORGANISM(S): Homo sapiens 
2014-11-13 | E-GEOD-59657 | biostudies-arrayexpress
UnknownWarfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.
Not available
S-EPMC2865873 | biostudies-literature
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
UnknownExtracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors.
Not available
S-EPMC10962646 | biostudies-literature
UnknownOutcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study.
Not available
S-EPMC8634634 | biostudies-literature
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