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TranscriptomicsSurvival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3b phosphorylation
Platelet-derived growth factor-CC (PDGF-CC) is the third member of the PDGF family discovered after more than two decades of studies on the original members of the family, PDGF-AA and PDGF-BB. The biological function of PDGF-CC remains largely to be explored. We report here a novel finding that PDGF...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-19207 | biostudies-arrayexpress
TranscriptomicsC. elegans piRNAs are processed from capped-small RNAs transcribed at promoters throughout the genome
Piwi-interacting (pi) RNAs are a class of germline-expressed small RNAs that have been linked to epigenetic programming in metazoa. C. elegans piRNAs known as 21U-RNAs are defined by more than 15,000 genome-encoded species. To explore the origin of 21U-RNAs we employed methods to enrich the 5' ends ...
ORGANISM(S): Mus musculus 
2012-12-22 | E-GEOD-40053 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of oral squamous cell carcinoma (OSCC)
According to epidemiological studies, a vast majority, approximately 80%~90% of male OSCC patients in Taiwan habitually drink alcohol (A), and chew betel quid (B), and use cigarette (C). To assess the impact of these dietary factors on the transcriptom, we conduct a high-throughput screen survey in ...
ORGANISM(S): Homo sapiens 
2013-05-02 | E-GEOD-37991 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Molecular Signature of Cholangiocarcinoma and Its Trandifferentation-Related Genes
Cholangiocarcinoma (CC) is an aggressive tumor that shows a poor survival rate even after resection. The present study aimed at identification of the genome-wide expressed genes related to CC oncogenesis and its sarcomatous transdifferentiation using DNA microarray technology. The differentially exp...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-22633 | biostudies-arrayexpress
UnknownComparison of Elixhauser and Charlson Methods for Predicting Oral Cancer Survival.
Not available
S-EPMC4998653 | biostudies-literature
TranscriptomicsLenalidomide-mediated enhanced translation of C/EBP?-p30 protein upregulates expression of the anti-leukemic microRNA-181a in acute myeloid leukemia - microRNA Data
Recently, we showed that increased miR-181a expression was associated with improved outcomes in cytogenetically normal acute myeloid leukemia (CN-AML). Interestingly, miR-181a expression was increased in CN-AML patients harboring CEBPA mutations, which are usually biallelic and associate with better...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-MTAB-1320 | biostudies-arrayexpress
UnknownThe Opposing Roles of IVS2+691 CC Genotype and AC/AG Diplotype of 118A>G and IVS2+691G>C of OPRM1 Polymorphisms in Cold Pain Tolerance Among Opioid-Dependent Malay Males on Methadone Therapy.
Not available
S-EPMC4676768 | biostudies-literature
TranscriptomicsExtensive effects of in vitro oocyte maturation on rhesus monkey cumulus cell transcriptome
The elaboration of a quality oocyte is integrally linked to the correct developmental progression of cumulus cell phenotype. In humans and non-human primates, oocyte quality is diminished with in vitro maturation. To determine the changes in gene expression in rhesus monkey cumulus cells (CC) that o...
ORGANISM(S): Macaca mulatta 
2011-05-22 | E-GEOD-25288 | biostudies-arrayexpress
UnknownEffect of a c-MYC Gene Polymorphism (g.3350G>C) on Meat Quality Traits in Berkshire.
Not available
S-EPMC4647093 | biostudies-literature
UnknownPhase Ib study of combinations of avadomide (CC-122), CC-223, CC-292, and rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma.
Not available
S-EPMC9176062 | biostudies-literature
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