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ProteomicsAnti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
Cancers with activating mutations of KRAS show a high prevalence and poor prognosis but remain intractable, requiring innovative strategies to overcome the poor targetability of KRAS. Here, we report that KRAS expression was post-translationally up-regulated through the deubiquitination of KRAS prot...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051954 | Pride
Kras protein deubiquitination  ndrg3  usp9x  pancreatic cancer 
UnknownConcomitant therapy achieved the best eradication rate for Helicobacter pylori among various treatment strategies.
Not available
S-EPMC4284355 | biostudies-literature
ProteomicsAnti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
Cancers with activating mutations of KRAS show a high prevalence and poor prognosis but remain intractable, requiring innovative strategies to overcome the poor targetability of KRAS. Here, we report that KRAS expression was post-translationally up-regulated through the deubiquitination of KRAS prot...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052379 | Pride
Kras protein deubiquitination  ndrg3  usp9x  pancreatic cancer 
TranscriptomicsTranscriptome sequencing for cancer stem cell properties in MCF-7 cells with knocked down CD24
CD24 is the one of cell surface protein that anchored via glycosyl phosphatidylinositol that links to cell surface and modulates growth and differentiation signal many of cell types. A small population of cells, namely M-bM-^@M-^XCancer Stem Cells (CSCs)M-bM-^@M-^Y, charges highly aggressive and met...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-61917 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of the Zebrafish Mind Bomb Mutant
To identify the genes differentially expressed in the zebrafish mibta52b mutant, genome-wide transcriptome analysis was performed using Serial Analysis of Gene Expression (SAGE). 335 transcripts were identified whose expressions were significantly altered in the mibta52b mutant as compared with the ...
ORGANISM(S): Danio rerio 
2008-10-08 | E-GEOD-13050 | biostudies-arrayexpress
TranscriptomicsDown-regulation as the dominant hippocampal gene expression profile with voluntary resistance wheel running by DNA microarray analysis
Exercise improves brain function enhancing neuronal plasticity and cognitive enhancement. For voluntary resistance wheel running (RWR) exercise, with a load of 30% of body weight, we reported enhancement of neurogenesis and spatial memory associated with hippocampal brain-derived neurotrophic factor...
ORGANISM(S): Rattus norvegicus 
2014-10-09 | E-GEOD-52516 | biostudies-arrayexpress
TranscriptomicsExpression profiles from HEK293 cells by overexpression of TRPM7 channel
The functional activity of TRPM7 is essential for cell viability and growth, and its expression is up-regulated in certain pathological conditions. In order to assess the effects of TRPM7 activity on cellular gene expression, inducible HEK293 cell-lines harboring the wild-type mouse TRPM7 and a muta...
ORGANISM(S): Homo sapiens 
2011-07-22 | E-GEOD-23102 | biostudies-arrayexpress
UnknownPrognostic Accuracy of SpO2-based Respiratory Sequential Organ Failure Assessment for Predicting In-hospital Mortality.
Not available
S-EPMC10754194 | biostudies-literature
UnknownTRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.
Not available
S-EPMC4735692 | biostudies-literature
UnknownVisualization of Synthetic Vascular Smooth Muscle Cells in Atherosclerotic Carotid Rat Arteries by F-18 FDG PET.
Not available
S-EPMC5539104 | biostudies-literature
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