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UnknownRhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer.
We conducted an RNA sequencing study to identify novel gene fusions in 80 discovery dataset tumors collected from young patients with diffuse gastric cancer (DGC). Twenty-five in-frame fusions are associated with DGC, three of which (CLDN18-ARHGAP26, CTNND1-ARHGAP26, and ANXA2-MYO9A) are recurrent i...
S-EPMC6202325 | biostudies-literature
UnknownModulatory Effect of Blood LDL Cholesterol on the Association between Cerebral Aβ and Tau Deposition in Older Adults.

Background

This study investigates the synergistic relationship between blood low-density lipoprotein cholesterol (LDL-C) and cerebral beta-amyloid (Aβ) in relation to tau deposition, a key factor in the pathology of Alzheimer's disease (AD), in older adults across a diverse cognitive spectr...
S-EPMC11573824 | biostudies-literature
ModelsWidiastuti2010 - Genome-scale metabolic network Zymomonas mobilis (iZM363)
Widiastuti2010 - Genome-scale metabolic network Zymomonas mobilis (iZM363) This model is described in the article: Genome-scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis. Widiastuti H, Kim JY, Selvarasu S, Karimi IA, Kim H, Seo JS, Lee DY. ...
2015-07-30 | MODEL1507180057 | BioModels
TranscriptomicsEffect of NDRG3 overexpression on cell response to hypoxia
Analysis of HeLa cells overexpressing NDRG3 or exposed to hypoxic condition. Gene expression profiles of HeLa cells stably expressing NDRG3 were compared to gene expression profiles of HeLa stable cells expressing mock or hypoxia-mediated gene expression profiles.
ORGANISM(S): Homo sapiens 
2015-07-24 | E-GEOD-55211 | biostudies-arrayexpress
TranscriptomicsEffect of NDRG3 or HIF-1α knockdown on cell response to hypoxia
Analysis of Huh-7 hepatocarcinoma cell line depleted of NDRG3 or HIF-1α under hypoxic condition. HIF-1α and NDRG3 have distinct functions in hypoxia responses. Results provide insight into molecular basis of HIF-independent signaling in the development and progression of hypoxic tumors Gene expressi...
ORGANISM(S): Homo sapiens 
2015-07-24 | E-GEOD-55212 | biostudies-arrayexpress
TranscriptomicsGenomic copy number alterations as predictive markers of systemic recurrence in breast cancer
Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess copy number changes in 31 pairs of clinicopathologically well matched recurred / nonrecurred breast cancer tissues. Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess c...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10128 | biostudies-arrayexpress
TranscriptomicsGenomic copy number alterations as predictive markers of neoadjuvant chemotherapy response in breast cancer
Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess different copy number changes between chemotherapy responsive and non-resposive breast cancer tissues. Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess different copy...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10129 | biostudies-arrayexpress
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Mouse liver assays)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-02 | MTBLS1266 | MetaboLights
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Standard mixture assay)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-05 | MTBLS1311 | MetaboLights
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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