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Synphilin-1, a major component of Lewy bodies in the brain of Parkinsons disease (PD) patients, is a cytoplasmic protein that interacts with alpha-synuclein and is suggested to have cytoprotective effects in the neuronal cells. alpha-Synuclein overexpression induced re-entry of the neuronal cells in...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2022-07-20 | MSV000089926 | MassIVE
Exposure to nanoparticles leads to their accumulation in the brain, but drug development to counteract this nanotoxicity remains challenging. Here we assessed the effect of silica-coated-magnetic nanoparticles containing the rhodamine B isothiocyanate dye [MNPs@SiO2(RITC)] on microglia through integ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD020225 | Pride
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