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TranscriptomicsRNA-seq profiling of microdissected rat renal tubule segments
We sequenced mRNAs from glomeruli and 14 different rat renal tubule segments collected by hand microdissection. Collagenase-digested rat renal tubule segments were collected by hand microdissection. Poly(A)-mRNAs were captured from cell lysate and sequenced using paired-end protocol.
ORGANISM(S): Rattus norvegicus 
2015-03-31 | E-GEOD-56743 | biostudies-arrayexpress
TranscriptomicsIdentification of transcripts predominantly expressed in cultured chicken primordial germ cells and embryonic fibroblasts.
The present investigation was to identify the signaling and metabolic pathways of expressed genes by microarray comparison between Primordial Germ Cells (PGCs) and their somatic counterpart, chicken embryonic fibroblasts (CEFs). We identified a total of 2,605 expressed transcripts. Among these, 1,19...
ORGANISM(S): Gallus gallus 
2013-01-10 | E-GEOD-38168 | biostudies-arrayexpress
ProteomicsIFI35 suppresses the transcription of hepatitis B virus cccDNA minichromosome via promoting HNF4α proteasomal degradation
Hepatitis B virus (HBV) infection is a major health problem with hundreds of millions of people still chronically infected worldwide. Although it is known that cytokines can inhibit HBV replication in infected hepatocytes, much is still unknown about the underlying mechanisms or mediators. In this s...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD066477 | Pride
Human Hbv Proteomics 
TranscriptomicsMus musculus hematopoietic stem cell
A transcriptome study in mouse hematopoietic stem cells was performed using a sensitive SAGE method, in an attempt to detect medium and low abundant transcripts expressed in these cells. Among a total of 31,380 unique transcript, 17,326 (55%) known genes were detected, 14,054 (45%) low-copy transcri...
ORGANISM(S): Mus musculus 
2009-05-20 | E-GEOD-16139 | biostudies-arrayexpress
TranscriptomicsIdentification of Murine Uterine Genes Regulated in a Ligand-Dependent Manner by the Progesterone Receptor.
Progesterone (P4) acting through its cognate receptor, the progesterone receptor (PR), plays an important role in uterine physiology. The PR knockout (PRKO) mouse has demonstrated the importance of the P4-PR axis in the regulation of uterine function. To define the molecular pathways regulated by P4...
ORGANISM(S): Mus musculus 
2012-08-06 | E-GEOD-39920 | biostudies-arrayexpress
TranscriptomicsTranscription array by profiling in WT and SRC-2 null mouse liver
The molecular targets of SRC-2 regulation in the murine liver stimulate fatty acid degradation and glycolytic pathway while fatty acid, cholesterol, and steroid biosynthetic pathways are down-regulated. A genomic approach using microarray analysis was employed to identify the subsets of genes that a...
ORGANISM(S): Mus musculus 
2014-02-14 | E-GEOD-55002 | biostudies-arrayexpress
TranscriptomicsRegulation of Angiogenesis by EZH2
While VEGF-targeted therapies are showing promise in clinical studies, new angiogenesis targets are needed to make additional gains. Here, we show that increased Zeste homologue 2 (EZH2) expression in either tumor cells or in tumor vasculature is predictive of poor clinical outcome. The increase in ...
ORGANISM(S): Homo sapiens 
2010-10-12 | E-GEOD-20381 | biostudies-arrayexpress
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
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