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MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
MetabolomicsSnail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
TranscriptomicsThe responses of astrocytes stimulated by extracellular a-synuclein
Abnormal neuronal aggregation of a-synuclein is implicated in the development of Parkinson’s disease. Glial cells also show extensive a-synuclein pathology and are thought to contribute to disease progression. However, the mechanism that produces the glial a-synuclein pathology and the interaction b...
ORGANISM(S): Rattus norvegicus 
2010-01-11 | E-GEOD-11574 | biostudies-arrayexpress
ProteomicsPGRC Cancer Proteome Study of Gastric Tissue
The goal of the project is to analyze different layers of proteome information including protein abundance and post-translational modifications of PGRC gastric tissue samples. Three pairs of human gastric cancer and adjacent normal tissues were extensively characterized by serial enrichments of phos...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080818 | MassIVE
UnknownMutation spectrum and frequency of copy number variations of the ANOS1 gene in patients with Kallmann syndrome or normosmic isolated hypogonadotropic hypogonadism.
Not available
S-EPMC10160557 | biostudies-literature
TranscriptomicsRNA-Seq analysis of quorum sensing-dependent genes in Burkholderia glumae BGR1
Burkholderia glumae causes rice grain rot and sheath rot by producing toxoflavin, whose expression is regulated by quorum sensing (QS). The QS systems of the bacterium rely on N-octanoyl homoserine lactone, synthesized by TofI and its cognate receptor TofR, to activate toxoflavin biosynthesis genes ...
ORGANISM(S): Burkholderia glumae 
2012-03-14 | E-GEOD-36485 | biostudies-arrayexpress
UnknownSTAT3-mediated IGF-2 secretion in the tumour microenvironment elicits innate resistance to anti-IGF-1R antibody.
Not available
S-EPMC4608384 | biostudies-literature
TranscriptomicsMus musculus hematopoietic stem cell
A transcriptome study in mouse hematopoietic stem cells was performed using a sensitive SAGE method, in an attempt to detect medium and low abundant transcripts expressed in these cells. Among a total of 31,380 unique transcript, 17,326 (55%) known genes were detected, 14,054 (45%) low-copy transcri...
ORGANISM(S): Mus musculus 
2009-05-20 | E-GEOD-16139 | biostudies-arrayexpress
Unknown[Study on the Necessity and Methodology for Enhancing Outpatient and Clinical Education in the Department of Radiology].
Not available
S-EPMC11625846 | biostudies-literature
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