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ProteomicsPhosphoproteomic analysis reveals enhanced PKA signaling in aged skeletal muscle is suppressed by caloric restriction
Although caloric restriction (CR) was first shown to extend the lifespan of rodents over 75 years ago, the underlying mechanisms remain unclear. Additionally, the majority of published studies have focused on the effects of short-term CR. To better understand cell signaling alterations in a tissue k...
ORGANISM(S): Mus Musculus (mouse) 
2021-01-30 | PXD018455 | JPOST Repository
TranscriptomicsThe RpoN Regulon of Escherichia coli O157:H7
There is increasing evidence to support a role for sigma factor 54 (RpoN) in the regulation of stress resistance factors and protein secretion systems important to bacterial transmission and pathogenesis. In enterohemorrhagic E. coli O157:H7, acid resistance and type III secretion are essential det...
ORGANISM(S): Escherichia coli O157:H7 str. Sakai 
2009-08-08 | E-GEOD-17467 | biostudies-arrayexpress
UnknownClinical significance of peripheral T-cell repertoire in head and neck squamous cell carcinoma treated with cetuximab and nivolumab.
Not available
S-EPMC11890688 | biostudies-literature
TranscriptomicsSequencing of reaction products from protospacer integration by Cas1-Cas2
We report the sites of protospacer integration into plasmids by Cas1-Cas2. The goal of this study is to determine the role of sequence elements on protospacer integration. Methods: Cas1-Cas2 integration products were fragmented, end-repaired, adapter ligated, PCR amplified, and analyzed by Illumina ...
ORGANISM(S): Cloning vector pUC19 
2015-01-30 | E-GEOD-64552 | biostudies-arrayexpress
UnknownT cell repertoire in peripheral blood as a potential biomarker for predicting response to concurrent cetuximab and nivolumab in head and neck squamous cell carcinoma.
Not available
S-EPMC9185557 | biostudies-literature
UnknownEosinophil deficiency compromises parasite survival in chronic nematode infection.
Not available
S-EPMC3923382 | biostudies-literature
UnknownSouthwest Oncology Group S0008: a phase III trial of high-dose interferon Alfa-2b versus cisplatin, vinblastine, and dacarbazine, plus interleukin-2 and interferon in patients with high-risk melanoma--an intergroup study of cancer and leukemia Group B, Children's Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group.
Not available
S-EPMC4226807 | biostudies-literature
UnknownRacial and Ethnic Disparities in Prostate Cancer Outcomes in the Veterans Affairs Health Care System.
Not available
S-EPMC8767437 | biostudies-literature
UnknownClinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling.
Not available
S-EPMC2597136 | biostudies-literature
UnknownThe effects of palbociclib in combination with radiation in preclinical models of aggressive meningioma.
Not available
S-EPMC8325754 | biostudies-literature
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