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TranscriptomicsTranscription profiling of E.coli biofilms treated with 7-hydroxyindole and isatin
For the microarray experiments, 10 g glass wool (Corning Glass Works, Corning, N.Y.) were used to form biofilms (30) in 250 mL in 1 L Erlenmeyer shake flasks which were inoculated with overnight cultures diluted that were 1:100. For EHEC with 7-hydroxyindole and isatin, 1000 mM 7-hydroxyindole in 2...
ORGANISM(S): Escherichia coli 
2008-06-14 | E-GEOD-6195 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli planktonic samples exposed to cis-1,2-dichloroethylene (cis-DCE)
Metabolically-engineered Escherichia coli has been used previously to degrade the ubiquitous pollutant cis-1,2-dichloroethylene (cis-DCE), and the impact of the metabolic engineering was assessed by investigating the changes in the proteome. Here, genome-wide transcriptome analysis was performed to...
ORGANISM(S): Escherichia coli 
2009-11-27 | E-GEOD-13698 | biostudies-arrayexpress
TranscriptomicsThe effect of IAN on P. aeruginosa virulence
Intercellular signal indole and its derivative hydroxyindoles inhibit Escherichia coli biofilm and diminish Pseudomonas aeruginosa virulence. However, indole and bacterial indole derivatives were unstable in microbial community due to the widespread of diverse oxygenases that could quickly degrade ...
ORGANISM(S): Pseudomonas aeruginosa 
2011-02-20 | E-GEOD-21508 | biostudies-arrayexpress
TranscriptomicsIdentification of Biofilm Inhibitors from Streptomyces Strains for Reducing Pseudomonas aeruginosa Biofilm Formation
Biofilms are ubiquitous in natural, medical, and engineering environments. While most antibiotics that primarily aim to inhibit cell growth may result in bacterial drug resistance, biofilm inhibitors do not affect cell growth and there is less chance of developing resistance. This work sought to id...
ORGANISM(S): Pseudomonas aeruginosa 
2013-03-21 | E-GEOD-28194 | biostudies-arrayexpress
TranscriptomicsThe Apple Flavonoid Phloretin Inhibits Escherichia coli O157:H7 Biofilm Formation and Ameliorates Colon Inflammation in Rat
Pathogenic biofilms have been associated with persistent infections due to high resistance to antimicrobial agents while commensal biofilms often fortify host immune system. Hence, controlling biofilm formation of both pathogenic bacteria and commensal bacteria is important in bacteria-related dise...
ORGANISM(S): Escherichia coli 
2011-11-22 | E-GEOD-28144 | biostudies-arrayexpress
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