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The present study was undertaken to discover molecular markers in bovine cumulus cells predictive of oocyte competence and elucidate their functional significance. Differences in RNA transcript abundance in cumulus cells harvested from oocytes of adult versus prepubertal animals (model of poor oocy...
ORGANISM(S): Bos taurus 
We explored potential bypass mechanisms to PI3K/mTOR-directed therapy in KRAS mutant CRC models, utilizing genetically engineered mouse models (GEMM) to generate acquired resistance to the targeted dual PI3K/mTOR small molecule inhibitor PF-04691502. Transcriptomic analysis revealed a dynamic stem-l...
ORGANISM(S): Mus musculus 
The files are associated with a manuscript submitted for publication by Jamie Lee Fritz et al. The main goal of this paper was to identify potential substrates for LKB1, a master kinase that is required for epithelial ovarian cancer spheroid viability and metastasis.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085415 | MassIVE
The files are associated with a manuscript submitted for publication by Jamie Lee Fritz et al. The main goal of this paper was to identify potential substrates for LKB1, a master kinase that is required for epithelial ovarian cancer spheroid viability and metastasis. Both Peak List and Results file...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-08 | MSV000085252 | MassIVE
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