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TranscriptomicsTranscription profiling of E. coli K-12 mutants yceP, trpE, and tnaA biofilm cell 24 hr
Gene expression of (i) K-12 yceP biofilms upon addition of 600 µM indole in LB glu medium, (ii) K-12 biofilms due to the trpE mutation in LB glu medium, and (iii) K-12 biofilms due to the tnaA mutation in LB medium. Experiment Overall Design: Strains:E. coli K12 BW25113 delta yceP, trpE, tnaA and w...
ORGANISM(S): Escherichia coli 
2008-06-13 | E-GEOD-4562 | biostudies-arrayexpress
TranscriptomicsComparison between wild type E. coli and adhE (alcohol dehydrogenase) mutants, grown under anaerobic condition
To characterize anaerobic stress-induced expression in adhE mutants, the microarray experiment was performed with two serotypes of wild type E. coli and their adhE mutants: (1) K-12 strain, wild type; (2) B strain, wild type; (3) BW25113, adhE mutants; (4) BL21(DE3), adhE mutants. Under anaerobic gr...
ORGANISM(S): Escherichia coli BL21(DE3) 
2014-09-26 | E-GEOD-46455 | biostudies-arrayexpress
TranscriptomicsHoneys Inhibit Virulence and Biofilm Formation in Enterohaemorrhagic Escherichia coli O157:H7, but Do not Harm Commensal Escherichia coli K-12 Biofilm
Honey has been widely used against bacterial infection for centuries. Previous studies suggested that honeys in high concentrations inhibited bacterial growth due to the presence of anti-microbial compounds, such as methylglyoxal, hydrogen peroxide, and peptides. In this study, we found that three...
ORGANISM(S): Escherichia coli 
2012-03-30 | E-GEOD-28193 | biostudies-arrayexpress
UnknownKL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease.
Not available
S-EPMC8219708 | biostudies-literature
TranscriptomicsEngineering Corynebacterium glutamicum for fast production of lysine and pipecolic acid
The Gram-positive soil bacterium Corynebacterium glutamicum is widely used in industrial fermentative processes for the production of amino acids. The world production of L-lysine has surpassed 2 million tons per year. Glucose is taken up into the C. glutamicum cell by the phosphotransferase system ...
ORGANISM(S): Corynebacterium glutamicum 
2016-03-30 | E-GEOD-79690 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Escherichia coli K-12 and ada mutant
Alkylation damage to DNA occurs when cells encounter alkylating agents in the environment or when active alkylators are generated by nitrosation of amino acids in metabolic pathways. To cope with DNA alkylation damage, cells have evolved genes that encode proteins with alkylation-specific DNA repair...
ORGANISM(S): Escherichia coli K-12 
2010-09-09 | E-GEOD-16565 | biostudies-arrayexpress
TranscriptomicsFUNCTIONAL ANALYSIS OF CTCF DURING MAMMALIAN LIMB DEVELOPMENT_ ChIP-chip
Limb buds were dissected from E10.75 mouse embryos, fixed in 1% formaldehyde for 15 min at room temperature, washed 3 times with cold PBS and stored at -800C. Pools of 16 limb buds were used for each ChIP-chip experiment. ChIP was performed according to (Lee et al., 2006) using 2 ?g of anti-CTCF ant...
ORGANISM(S): Mus musculus 
2011-11-01 | E-MEXP-2979 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E.coli biofilms treated with 7-hydroxyindole and isatin
For the microarray experiments, 10 g glass wool (Corning Glass Works, Corning, N.Y.) were used to form biofilms (30) in 250 mL in 1 L Erlenmeyer shake flasks which were inoculated with overnight cultures diluted that were 1:100. For EHEC with 7-hydroxyindole and isatin, 1000 mM 7-hydroxyindole in 2...
ORGANISM(S): Escherichia coli 
2008-06-14 | E-GEOD-6195 | biostudies-arrayexpress
ProteomicsPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
Mitochondia Pptc7 Phosphoproteome 
TranscriptomicsGene expression profiling of advanced murine K-RasG12V lung adenocarcinomas
We aimed to analyze the transcriptional profile of full-blown murine lung adenocarcinomas driven by K-RasG12V oncogene. We used a GEM model of lung adenocarcinoma driven by a resident K-RasG12V oncogene. On average, tumors were collected 10 months after Adeno-CRE infection.
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-65257 | biostudies-arrayexpress
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