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ProteomicsFritz_STK11KO_MIB_2020_TripleTOF5600_complete
The files are associated with a manuscript submitted for publication by Jamie Lee Fritz et al. The main goal of this paper was to identify potential substrates for LKB1, a master kinase that is required for epithelial ovarian cancer spheroid viability and metastasis.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-15 | MSV000085415 | MassIVE
ProteomicsFritz_STK11KO_MIB_2020_TripleTOF5600
The files are associated with a manuscript submitted for publication by Jamie Lee Fritz et al. The main goal of this paper was to identify potential substrates for LKB1, a master kinase that is required for epithelial ovarian cancer spheroid viability and metastasis. Both Peak List and Results file...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-08 | MSV000085252 | MassIVE
TranscriptomicsTranscription profiling of mouse spinal chord from a mouse model of severe spinal muscular atrophy
Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy
ORGANISM(S): Mus musculus 
2009-12-07 | E-MEXP-2428 | biostudies-arrayexpress
TranscriptomicsGeneration and purification of Th1 and Th2 effector and memory CD4+ T cells
Naïve CD4+ T cells were isolated from spleen of AND TcR transgenic/green fluorescence protein (GFP) transgenic mice (Kaye et al., Nature 1989;341:746, Wright et al, Blood 2001;97:2278) that recognize a peptide of pigeon cytochrome C in the context of I-Ek and express CD44lo, CD62Lhi, CD45RBhi, and ...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-8352 | biostudies-arrayexpress
TranscriptomicsAn epithelial-mesenchymal transition (EMT) gene signature predicts resistance to erlotinib and PI3K pathway inhibitors and identifies Axl as a novel EMT marker in non-small cell lung cancer.
Epithelial/mesenchymal transition (EMT) is associated with loss of cell adhesion molecules, such as E-cadherin, and increased invasion, migration, and proliferation in epithelial cancers. In non-small cell lung cancer (NSCLC), EMT is associated with greater resistance to EGFR inhibitors. However, it...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-33072 | biostudies-arrayexpress
TranscriptomicsSubstitutions in the KRas oncogene determine protein behavior: Implications for signaling and clinical outcome.
Mutant KRAS (mut-KRAS) is present in 30% of all human cancers and plays a critical role in cancer cell growth and resistance to therapy. There is evidence from colon cancer that mut-KRAS is a poor prognostic factor and negative predictor of patient response to molecularly targeted therapy. However,...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-27389 | biostudies-arrayexpress
TranscriptomicsKrüppel-like factor 4 regulates T cell function
Krüppel-like factor 4 (Klf4), a transcription factor mediating context-dependent activation or repression, plays a key role in maintaining pluripotency of stem cells and in regulating cell differentiation. However, the precise function of Klf4 in T cell development and differentiation is largely unk...
ORGANISM(S): Mus musculus 
2011-06-24 | E-GEOD-24880 | biostudies-arrayexpress
UnknownQuantifying the reduction of airborne infectious viral load using a ventilated patient hood.
Not available
S-EPMC10125916 | biostudies-literature
GenomicsChIP-seq of CTCF, RAD21, and TOP2B binding sites in three human tissue samples with hepatocellular carcinoma
The roles of topoisomerases in somatic mutagenesis in cancer are poorly understood and their DNA-binding landscape remains largely unmapped. Here we generated genome-wide DNA-binding maps of TOP2B, CTCF, and RAD21 in human hepatocellular carcinoma samples.
ORGANISM(S): Homo sapiens 
2024-02-01 | E-MTAB-13301 | biostudies-arrayexpress
UnknownEffectiveness of portable air filtration on reducing indoor aerosol transmission: preclinical observational trials.
Not available
S-EPMC8481008 | biostudies-literature
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