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MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
UnknownPhase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.
Not available
S-EPMC5791841 | biostudies-literature
UnknownPhase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors.
Not available
S-EPMC5978471 | biostudies-literature
UnknownCediranib for metastatic alveolar soft part sarcoma.
Not available
S-EPMC3677840 | biostudies-literature
UnknownQuality of Life Outcomes for Cabozantinib Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma: METEOR Phase III Randomized Trial.
Not available
S-EPMC6804841 | biostudies-literature
UnknownROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.
Not available
S-EPMC7299545 | biostudies-literature
UnknownRandomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.
Not available
S-EPMC6085179 | biostudies-literature
UnknownHistopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model.
Not available
S-EPMC8686255 | biostudies-literature
UnknownPreexisting Skin-Resident CD8 and γδ T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy.
Not available
S-EPMC11954000 | biostudies-literature
OtherIdentification of SUMO-2/3 modified proteins associated with mitotic chromosomes.
Data from Massive, ID: MSV000078890, PXD ID: PXD001534. File: MM_8A2_SUMO23_mitosis_C_75KDa_v1.mzml. Published as part of Proteomics. 2014 Nov 4 . From the Abstract: {{i}} ... In this study, we used chromosome spreads to more precisely define the localization of SUMO-2/3 to the inner-centromere and...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310005148 | GPMDB
Resource Reanalysis 
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