Lee S K SK - OmicsDI

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Unknown (1590)
Genomics (60)
Proteomics (24)
Transcriptomics (22)
Metabolomics (5)
Multiomics (2)

Organisms

Homo sapiens (84)
Mus musculus (12)
Caenorhabditis elegans (2)
Neurospora crassa (1)
Drosophila melanogaster (1)
Escherichia coli (1)
Chlorocebus sabaeus (1)
Mus (1)
Staphylococcus aureus (1)

Repository

EGA (57)
biostudies-arrayexpress (27)
pride (15)
MassIVE (7)
MetaboLights (5)
jPOST (1)

Tissue

Brain (4)
Cell culture (3)
Epithelial cell (2)
Kidney (2)
Lung (2)
Adrenal gland (1)
B-lymphocyte (1)
Blood (1)
Blood platelet (1)
Colon (1)
Cytotoxic T-lymphocyte (1)
Esophagus (1)
Fibroblast (1)
Follicular fluid (1)
Frontal lobe (1)
Gall bladder (1)
Gut (1)
Hair shaft (1)
Heart (1)
Helper T-lymphocyte (1)
Liver (1)
Monocyte (1)
Natural killer cell (1)
Ovary (1)
Pancreas (1)
Placenta (1)
Pluripotent stem cell (1)
Prostate gland (1)
Rectum (1)
Retina (1)

Disease

Hepatomegaly (1)
"hepatocellular adenoma" (1)
Normal (1)
Breast cancer (1)
COVID-19 (1)

Technology Type

Mass Spectrometry (15)
Shotgun proteomics (10)
Mass spectrometry (4)
Bottom-up proteomics (4)
Data-dependent acquisition (2)
Illumina OncoArray (1)
NMR spectroscopy (1)
Gel-based experiment (1)

Instrument Platform

LTQ Orbitrap (3)
Liquid Chromatography MS - positive - reverse phase (3)
LTQ Orbitrap Elite (2)
Liquid Chromatography MS - negative - reverse phase (2)
GenePix 4000B [Axon Instruments] (1)
NextSeq 500 (1)
LTQ (1)
LTQ Orbitrap Velos (1)
LTQ Orbitrap Velos Pro (1)
LTQ XL (1)
Q Exactive (1)
6540 Q-TOF LC/MS (Agilent) (1)
Bruker (1)

Publication Date

2016 (7)
2023 (5)
2011 (4)
2026 (4)
2014 (3)
2012 (3)
2009 (3)
2008 (3)
2015 (2)
2013 (2)
2007 (2)
2006 (2)
2005 (2)
2024 (2)
2022 (2)
2021 (2)
2025 (2)
2018 (2)
2010 (1)
2019 (1)

CHEBI ID

CHEBI:72747 (2)
CHEBI:132968 (1)
CHEBI:72742 (1)
CHEBI:185590 (1)
CHEBI:185033 (1)
CHEBI:185082 (1)
CHEBI:184433 (1)
CHEBI:185588 (1)
CHEBI:185586 (1)
CHEBI:185161 (1)
CHEBI:185584 (1)
CHEBI:184906 (1)
CHEBI:185183 (1)
CHEBI:185582 (1)
CHEBI:185580 (1)
CHEBI:184474 (1)
CHEBI:184829 (1)
CHEBI:185175 (1)
CHEBI:184782 (1)
CHEBI:185578 (1)
CHEBI:184420 (1)
CHEBI:185576 (1)
CHEBI:184776 (1)
CHEBI:184405 (1)
CHEBI:185575 (1)
CHEBI:185573 (1)
CHEBI:185571 (1)
CHEBI:185568 (1)
CHEBI:185013 (1)
CHEBI:185567 (1)

Metabolite Name

LysoPC(18:1[9Z]) (1)
Tetrahexosylceramide (d18:1/16:0) (1)
SM(d18:0/16:0) (1)
PS(DIME(11,5)/MONOME(13,5)) (1)
4,4,10-Trimethyl-1,11-bis(3-methylbut-2-en-1-yl)-10-(4-methylpent-3-en-1-yl)-9-(2-methylpropanoyl)-3-oxatricyclo[7.3.1.0²,⁷]trideca-2(7),5-diene-8,13-dione (1)
2-{[3,4-dihydroxy-5,6-bis({[(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoyl]oxy})oxan-2-yl]methoxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate (1)
{2-[(7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoyloxy]-3-(tetracosanoyloxy)propoxy}[2-(methylamino)ethoxy]phosphinic acid (1)
TG(20:1(11Z)/22:2(13Z,16Z)/20:2(11Z,14Z)) (1)
1-(8-{[6-({[3,5-dihydroxy-6-(hydroxymethyl)-4-{[3,4,5-trihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}oxan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-1-hydroxy-6-methoxy-3-methylnaphthalen-2-yl)ethan-1-one (1)
2-amino-4-({1-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2-({[3-(methylsulfanyl)propyl]thio(carbonoimidyl)}sulfanyl)ethyl}-C-hydroxycarbonimidoyl)butanoic acid (1)
(2E)-N-{2-[5,5'-dihydroxy-3'-(2-{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl}-3-(4-hydroxyphenyl)prop-2-enimidic acid (1)
(2R,3R)-2-(3,4-Dihydroxyphenyl)-6-[(2R,3R,4S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-4-yl]-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate (1)
2-(Hydroxymethyl)-6-[(3,4,5-trihydroxy-6-{[16-hydroxy-2,6,6,10,11-pentamethyl-14-(6-methyl-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hept-5-en-2-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-yl]oxy}oxan-2-yl)methoxy]oxane-3,4,5-triol (1)
5-(6-hydroxy-4-{5-[(E)-2-[6-hydroxy-3-(3-hydroxyphenyl)-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]ethenyl]-2-(4-hydroxyphenyl)-1-benzofuran-3-yl}-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl)benzene-1,3-diol (1)
6-(16'-{[3,4-dihydroxy-6-(hydroxymethyl)-5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosane]-15'-oloxy)-3,4,5-trihydroxyoxane-2-carboxylic acid (1)
3-[({2-[(3-{[4-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-1,2-dihydroxy-3,3-dimethylbutylidene]amino}-1-hydroxypropylidene)amino]ethyl}sulfanyl)carbonyl]-4-hydroxy-4-phenylbutanoic acid (1)
PC(O-22:1(13Z)/22:2(13Z,16Z)) (1)
4-({[({[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-2-hydroxy-N-[2-({2-[(11E)-icos-11-enoylsulfanyl]ethyl}-C-hydroxycarbonimidoyl)ethyl]-3,3-dimethylbutanimidic acid (1)
(1R,2R,3R,11S,12S,14R,26R)-5,6',7',12-tetrahydroxy-6-methoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1³,¹¹.0²,¹³.0⁴,⁹.0¹⁵,²³.0¹⁶,²⁰]triacontane-26,1'-isoquinoline]-4(9),5,7,15(23),16(20),21-hexaen-22-yl acetate (1)
Ps(14:1(9z)/20:5(5z,8z,11z,14z,17z)) (1)
2-[6'-(5,7-Dihydroxy-4-oxo-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-2-yl)-2',3',4,4',5,6-hexahydroxy-[1,1'-biphenyl]-2-yl]-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate (1)
Heptacosane-6,8-dione (1)
3,4,5-trihydroxy-6-{[5-hydroxy-14-(1-hydroxy-6-methylhept-5-en-2-yl)-2,11,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-1(10)-en-8-yl]oxy}oxane-2-carboxylic acid (1)
2-[(7-{[4,5-dihydroxy-6-(hydroxymethyl)-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate (1)
TG(15:0/22:5(4Z,7Z,10Z,13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (1)
2-[2-({7-[(3-carboxy-3-{2-[(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy]-2-oxoethyl}propanoyl)oxy]-11,16,18-trihydroxy-19-[(1-hydroxyethylidene)amino]-5,9-dimethylicosan-6-yl}oxy)-2-oxoethyl]butanedioic acid (1)
(6-{4-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-8-yl]-3,5,7-trihydroxy-2-(3-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-8-yl}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl)oxidanesulfonic acid (1)
[6,7,8,11,12,13,23-heptahydroxy-3,16-dioxo-21-(3,4,5-trihydroxybenzoyloxy)-2,17,20-trioxatetracyclo[17.3.1.0⁴,⁹.0¹⁰,¹⁵]tricosa-4,6,8,10,12,14-hexaen-22-yl]oxidanesulfonic acid (1)
N-Isobutyl-2E,4Z-octadecadienoyl amine (1)
PA(O-16:0/18:0) (1)

Study type

Transcription profiling by array (15)
Unknown experiment type (2)
ChIP-seq (2)
RNA-seq of non coding RNA (2)
Proteomic profiling by mass spectrometer (1)
4C (1)
Other (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of coding RNA (1)

Release Date

2021 (180)
2023 (169)
2024 (168)
2022 (167)
2025 (151)
2020 (128)
2019 (95)
2018 (89)
2015 (80)
2016 (76)
2017 (59)
2014 (50)
2013 (49)
2012 (46)
2011 (37)
2009 (20)
2026 (19)
2010 (15)
2008 (9)
2007 (6)
2006 (2)
2005 (2)

Lab affiliation

1Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea (1)
Associate Professor (1)
Associate Professor, Department of Laboratory Mediciene, UCSF (1)
Center for Biotechnology & Genomic Medicine, Augusta University, Augusta, GA, USA (1)
Center for Theragnosis, Korea Institute of Science and Technology, Republic of Korea (1)
Department of Applied Chemistry College of Applied Sciences, Kyung Hee University, Yongin-si, Gyeonggi-do, 446-701 (1)
Department of Medicine, Weill Cornell Medicine, New York, NY, USA (1)
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USA (1)
Nanyang Technological University, Singapore (1)
Proteomics and Metabolomics Core Facility, Biomedical Research Institute, Seoul National University Hospital (1)
QBI Director and Professor in Cellular and Molecular Pharmacology, UCSF (1)
School of Biological Science, Associate Professor Valerie Lin Chun Ling's research lab, Nanyang Technological University (SBS, NTU), Singapore (1)
Sequence database group (1)
Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore 138648, Singapore (1)
Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA, USA (1)

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NMR based metabolomics study of Y2 receptor activation by neuropeptide Y in the SK-N-BE2 human neuroblastoma cell line

Neuropeptide Y (NPY) and its Y2 receptors (Y2R) play an important role in regulating growth of various tumors and are highly expressed in human neuroblastoma brain tumors. Cell lines derived from neuroblastoma brain tumors provide a good model to study the consequences of NPY activation of Y2R in tu...

2014-10-01 | MTBLS104 | MetaboLights

4C sequencing for the SOX11 promoter in the neuroblastoma cell lines CLB-GA, KELLY, SK-N-AS and SH-EP

4C sequencing for the SOX11 promoter in the neuroblastoma cell lines CLB-GA, KELLY, SK-N-AS and SH-EP.

ORGANISM(S): Homo sapiens

2023-02-19 | E-MTAB-12580 | biostudies-arrayexpress

Transcription profiling by array of human SK-N-AS neuroblastoma xenograft tumor treated with anti-human IGF-IR monoclonal antibody (h10H5) to study the anti-tumour function of the antibody

The insulin-like growth factor (IGF) system consists of two ligands (IGF-I and IGF-II), which both signal through type I IGF receptor (IGF-IR) to stimulate proliferation and inhibit apoptosis, with activity contributing to malignant growth of many types of human cancers. We have developed a humanize...

ORGANISM(S): Homo sapiens

2008-10-25 | E-GEOD-11959 | biostudies-arrayexpress

Transcription profiling of mouse primary keratinocytes expressing Rho/CRIK to study the impact of Rho signaling pathway on gene expression.

Rho GTPases integrate control of cell structure and adhesion with downstream signaling events. In keratinocytes, RhoA is activated at early times of differentiation and plays an essential function in establishment of cell–cell adhesion. We report here that, surprisingly, Rho signaling suppresses dow...

ORGANISM(S): Mus musculus

2007-09-07 | E-GEOD-3162 | biostudies-arrayexpress

Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson's disease.

Not available

S-EPMC8873463 | biostudies-literature

A randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of adjunctive cenobamate in Asian patients with focal seizures.

Not available

S-EPMC12927683 | biostudies-literature

Metabolomic fingerprinting of bull spermatozoa for identification of fertility signature metabolites

The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...

2021-12-07 | MTBLS1071 | MetaboLights

The Establishment of K-CaP (the Multicenter Korean Prostate Cancer Database).

Not available

S-EPMC3630340 | biostudies-literature

Doubling Time of the COVID-19 Epidemic by Chinese Province.

Not available

S-EPMC7216847 | biostudies-literature

Synthesis and biological evaluation of potent benzoselenophene and heteroaromatic analogues of (S)-1-(chloromethyl)-8-methoxy-2,3-dihydro-1H-benzo[e]indol-5-ol (seco-MCBI).

Not available

S-EPMC9071829 | biostudies-literature