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TranscriptomicsC1 metabolism in Corynebacterium glutamicum: an endogenous pathway for oxidation of methanol to carbon dioxide
Methanol is considered as an interesting carbon source in biobased microbial production processes. As Corynebacterium glutamicum is an important host in industrial biotechnology, in particular for amino acid production, we performed studies on the response of this organism to methanol. C. glutamicum...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-09-27 | E-GEOD-49936 | biostudies-arrayexpress
TranscriptomicsThe ability of VSL#3 to restore the age-related deficit in LTP is associated with changes in brain genes expression
A deficit in synaptic plasticity is one of the many changes that occurs with age. Specifically the archetypal model of plasticity, long-term potentiation (LTP), is reduced in hippocampus of middle-aged and aged animals. Several factors are likely to contribute to this deficit including morphologic...
ORGANISM(S): Rattus norvegicus 
2014-04-02 | E-GEOD-51381 | biostudies-arrayexpress
TranscriptomicsVSL#3 protects against development of visceral pain in the neonatal maternal separation model: A whole genome microarray study
Background & Aims: Irritable bowel syndrome (IBS) is a disorder characterized by chronic abdominal pain and is linked to post-inflammatory and stress-correlated factors that cause changes in the perception of visceral events. Increased evidence indicates that probiotic bacteria may be useful in tre...
ORGANISM(S): Rattus norvegicus 
2013-06-26 | E-GEOD-38942 | biostudies-arrayexpress
TranscriptomicsDendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway
Dendritic cells (DCs) are crucial for sensing pathogens and triggering immune response. GM-CSF myeloid dendritic cells (GM-DCs) secrete several cytokines including IL-2 upon activation by pathogen associated molecular pattern (PAMP) ligands. DC IL-2 has been shown to be important for innate and adap...
ORGANISM(S): Mus musculus 
2015-05-21 | E-GEOD-58120 | biostudies-arrayexpress
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