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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
UnknownExploring natural variation for rice sheath blight resistance in Brachypodium distachyon.
Not available
S-EPMC6351096 | biostudies-literature
UnknownCoronatine inhibits stomatal closure and delays hypersensitive response cell death induced by nonhost bacterial pathogens.
Not available
S-EPMC3628748 | biostudies-literature
UnknownSuppression of plant defense responses by extracellular metabolites from Pseudomonas syringae pv. tabaci in Nicotiana benthamiana.
Not available
S-EPMC3648423 | biostudies-literature
ProteomicsReprogramming SREBP1-dependent lipogenesis and inflammation in high-risk breast with licochalcone A: a novel path to cancer prevention
This study investigates the effects of Licochalcone A (LicA) on protein stability in breast cancer cells using Proteome Integral Solubility Alterations (PISA) proteomics. We treated MCF-7 (ER+) and MDA-MB-231 (ER-) cells with LicA (10 µM) for 24 hours and subjected them to temperature-dependent prot...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD061086 | Pride
Proteomics Licochalcone a Lipid metabolism Breast cancer prevention Lc-ms Srebp Antiproliferation Proteome integral solubility alterations (pisa) Pi3k-akt pathway Metabolic reprogramming Anti-inflammation 
UnknownA transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants.
Not available
S-EPMC6548545 | biostudies-literature
UnknownFunctional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer.
Not available
S-EPMC8764204 | biostudies-literature
UnknownEnabling tumor-specific drug delivery by targeting the Warburg effect of cancer.
Not available
S-EPMC11866520 | biostudies-literature
UnknownHzf Determines cell survival upon genotoxic stress by modulating p53 transactivation.
Not available
S-EPMC2779720 | biostudies-literature
UnknownElevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas.
Not available
S-EPMC10529338 | biostudies-literature
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