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MetabolomicsSnail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
ProteomicsHuman lung adenocarcinoma tissue LC-MS/MS
This project is a report of a chromosome-based human proteome project focused on chromosome 9 (Chr 9). To reveal missing proteins and undiscovered features in proteomes, LC-MS/MS analysis based identification and characterization were conducted on 5 pairs of lung adenocarcinoma tumors and adjacent n...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079961 | MassIVE
TranscriptomicsPhysiologic Hypoxia Promotes Maintenance of CML Stem Cells Despite Effective BCRM-bM-^HM-^RABL1 Inhibition
ABL1 kinase inhibitors such as imatinib mesylate (IM) are effective in managing chronic myelogenous leukemia (CML) but incapable of eliminating leukemia stem cells (LSCs), suggesting that kinaseM-bM-^HM-^Rindependent pathways support LSC survival. Given that the bone marrow hypoxic microenvironment ...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-48294 | biostudies-arrayexpress
UnknownOncogenic pathway combinations predict clinical prognosis in gastric cancer.
Not available
S-EPMC2748685 | biostudies-literature
UnknownInvestigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures.
Not available
S-EPMC7269710 | biostudies-literature
UnknownIntegrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.
Not available
S-EPMC4062710 | biostudies-literature
UnknownTumor immune microenvironment delineates progression trajectories of distinct nasopharyngeal carcinoma phenotypes.
Not available
S-EPMC12208333 | biostudies-literature
UnknownGenetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.
Not available
S-EPMC6685441 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
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