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ProteomicsNicheProt: Cell-type-resolved proteomics of mouse spleen tissue compartments
This dataset contains proteomic analyses that validate the spatial proteomic technology, NicheProt, and its application to investigate dendritic cell phenotypes in inflammed mouse spleens. NicheProt is a 3D optical microscopy-guided, photobleaching-mediated cell barcoding approach to isolate intact ...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-19 | PXD075718 | Pride
Microscopy Dendritic cells Inflammation Cell barcoding Spatial proteomics 
ProteomicsEvaluation of protein artifacts in tissue cryopreservation
This dataset presents proteomic analyses validating the spatial proteomics technology, NicheProt. NicheProt is a 3D optical microscopy–guided, photobleaching-mediated cell barcoding approach for isolating intact cell types from defined microanatomical niches. Here, we evaluate whether tissue cryopre...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-19 | PXD075811 | Pride
ProteomicsEvaluation of protein artifacts in the NicheProt workflow
This dataset contains proteomic analyses that validate the spatial proteomics technology, NicheProt. NicheProt is a 3D optical microscopy–guided, photobleaching-mediated cell barcoding approach designed to isolate intact cell types from specific microanatomical niches. We evaluate the proteomic prof...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-19 | PXD075769 | Pride
UnknownCase report and review of the literature: immune dysregulation in a large familial cohort due to a novel pathogenic RELA variant.
Not available
S-EPMC9960492 | biostudies-literature
MetabolomicsComparison of lipidome profiles of Caenorhabditis elegans—results from an inter-laboratory ring trial

Introduction

Lipidomic profiling allows 100s if not 1000s of lipids in a sample to be detected and quantified. Modern lipidomics techniques are ultra-sensitive assays that enable the discovery of novel biomarkers in a variety of fields and provide new insight in mechanistic investigations. D...
2022-02-21 | MTBLS2016 | MetaboLights
GenomicsSubtelomeric p53 Binding Prevents Accumulation of DNA Damage at Human Telomeres
Telomeres and tumor suppressor protein TP53 (p53) function in genome protection, but a direct role of p53 at telomeres has not yet been described. Here, we have identified non-canonical p53 binding sites within the human subtelomeres that suppress the accumulation of DNA damage at telomeric repeat ...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-75528 | biostudies-arrayexpress
UnknownSpecific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines-an exploratory sub-study of the BRACE trial.
Not available
S-EPMC11058726 | biostudies-literature
UnknownRedox-active vitamin C suppresses human osteosarcoma growth by triggering intracellular ROS-iron-calcium signaling crosstalk and mitochondrial dysfunction.
Not available
S-EPMC11342202 | biostudies-literature
TranscriptomicsPrimary and adjacent non-malignant tissue samples of 100 HCC patients (mRNA)
Genome-wide mRNA expression profiles of 100 primary and matched non-malignant tissues of HCC patients from a Singapore patient cohort. HCC is a hetergenous disease and it is important to understand the underlying molecular mechanisms. Here, we studied the role of microRNAs in HCC by integrating micr...
ORGANISM(S): Homo sapiens 
2016-02-18 | E-GEOD-62043 | biostudies-arrayexpress
UnknownDe novo missense mutation in GRIA2 in a patient with global developmental delay, autism spectrum disorder, and epileptic encephalopathy.
Not available
S-EPMC9235849 | biostudies-literature
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