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GenomicsStretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells
T Cell stretch-enhancers are vulnerable to Jak inhibitor tofacitinib Treatment of T cells with the Janus kinase (JAK) inhibitor, tofacitinib, disproportionately altered the expression of RA risk genes with stretech-enhancer (SE) structures.
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-60482 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression profiling of different T cell subset in human tonsils
Tight control of follicular helper T(Tfh) cells is required for optimal maturation of the germinal center (GC) response. The molecular mechansims controlling Tfh cell differentiation remain incompletely understood. Here we sought to to identfiy miRNAs that might regulate Tfh cell development and/or ...
ORGANISM(S): Homo sapiens 
2015-01-10 | E-GEOD-64833 | biostudies-arrayexpress
UnknownFrom Deutsche Zeitschrift to International journal of legal medicine-100 years of legal medicine through the lens of journal articles, Part 4: International journal of legal medicine from 1990 to 2022.
Not available
S-EPMC10861393 | biostudies-literature
TranscriptomicsRNA-seq of murine cytotoxic T lymphocytes in response to myosin IIA inhibition using para-nitroblebbistatin
This project explores the effects of inhibiting myosin IIA using para-nitroblebbistatin (pNB) on effector cytotoxic T lymphocyte (CTL) activation. Effector CTLs were differentiated from OTI TCR transgenic mice for 7 days in vitro, then stimulated (or not stimulated) with anti-CD3 for 1 hour, treated...
ORGANISM(S): Mus musculus 
2025-09-27 | E-MTAB-14579 | biostudies-arrayexpress
UnknownArtificial Intelligence and Decision-Making in Oncology: A Review of Ethical, Legal, and Informed Consent Challenges.
Not available
S-EPMC12423120 | biostudies-literature
GenomicsDeep single-cell RNA sequencing data for 11138 T cells from tumour, adjacent normal tissue and peripheral blood of treatment-naive CRC patients. The DATA ACCESS AGREEMENT is provided at https://github.com/zhangyybio/single-T-cell-data-access. Applicants can request access to the data by directly downloading it or by sending an email to cancerpku@pku.edu.cn. The process that is used to approve an application includes verifying the institution, participants and research purposes of the application. In general this process will take about two weeks. In principal, any scientific research program complying with the laws and bioethic regulation policies of China will be approved.
T cells are central players in cancer immunotherapy1, yet some of their fundamental properties such as development and migration within tumours remain elusive. The enormous T cell receptor (TCR) repertoire, required for recognising foreign and self-antigens2,3, could serve as lineage tags to track t...
EGAS00001002791 | EGA
UnknownAnalysis of medico-legal claims related to deliveries: Caesarean section vs. vaginal delivery.
Not available
S-EPMC11575767 | biostudies-literature
UnknownNFκB attenuates IL-5 production and upregulates T-box transcription factors in Th2-like T cells.
Not available
S-EPMC3973803 | biostudies-literature
UnknownAlcohol consumption induces murine osteoporosis by downregulation of natural killer T-like cell activity.
Not available
S-EPMC8589379 | biostudies-literature
UnknownThe impact of the U.S federal minimum legal drinking age law on alcohol involved firearm suicide: a regression discontinuity approach.
Not available
S-EPMC11773202 | biostudies-literature
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