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ProteomicsRepurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus
To combat methicillin-resistant Staphylococcus aureus (MRSA) infections novel drugs are desperately needed. From a screen, we found that the anti-cancer drug sorafenib effectively kills MRSA strains. By synthetic variation of key structural features, we identified a potent analog, PK150, exhibiting ...
ORGANISM(S): Staphylococcus aureus 
2019-09-09 | PXD012946 | Pride
Full proteome Affinity-based protein profiling (afbpp) Q exactive plus Chemical proteomics Staphylococcus aureus subsp. aureus nctc 8325 Secretome Surfaceome Orbitrap fusion 
UnknownB Cells and B Cell Blasts Withstand Cryopreservation While Retaining Their Functionality for Producing Antibody.
Not available
S-EPMC6028916 | biostudies-literature
GenomicsWGSeq_HealthyHuman_DATA_SET_xmas_MB_2013_07_10 - samples
HSC73_clone: Bone marrow mononuclear cells from the healthy 73 years old female were thawed and labeled with Alexa-Fluor 488-conjugated anti-CD34 (581, Biolegend), Alexa-Fluor 700-conjugated anti-CD38 (HIT2, eBioscience), a cocktail of APC-conjugated lineage antibodies consisting of anti-CD4 (RPA-T4...
EGAD00001000666 | EGA
GenomicsHypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19
In coronavirus disease 2019 (COVID-19), hypertension and cardiovascular diseases are major risk factors for critical disease progression. However, the underlying causes and the effects of the main anti-hypertensive therapies-angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor b...
EGAS00001004772 | EGA
2019 novel coronavirus infection 2019-nCoV infection coronavirus disease 2019 COVID-19 SARS-coronavirus 2 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 
Genomicsrna_seq_data_freeze_march_2013_DATA_SET_MMML_2012_11_06 - samples
ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing
EGAD00001000356 | EGA
GenomicsMMML_2012_11_06_Methylation450k_case - samples
DNA methylation analysis of 6 primary lymphoma samples
EGAD00010000377 | EGA
GenomicsWGSeq_RNAseq_ChIPseq_Cancer_ICGC_DATA_SET_xmas_MB_2013_07_10 - samples
Whole Genome Seq: Illumina HiSeq sequence data (with >30x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. Paired-end RNA sequencing reads were mapp...
EGAD00001000664 | EGA
GenomicsRNA-Seq_DATA_SET_storm_MMML_2013_07_10 - samples
ICGC MMML-seq Data Freeze July 2013 transcriptome sequencing
EGAD00001000648 | EGA
Genomicswgs_data_freeze_march_2013_DATA_SET_MMML_2012_11_06 - samples
ICGC MMML-seq Data Freeze March 2013 whole genome sequencing
EGAD00001000355 | EGA
Genomicswgs_DATA_SET_MMML_2012_11_06 - samples
ICGC MMML-seq Data Freeze November 2012 whole genome sequencing
EGAD00001000278 | EGA
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