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Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
A forward genetics screen led to the identification of the putative chromatin regulator EDM2 as a cellular anti-silencing factor and regulator of genome DNA methylation patterns. EDM2 contains a composite PHD finger domain that recognizes both active H3K4 and repressive H3K9 methylation marks at the...
ORGANISM(S): Arabidopsis thaliana 
In eukaryotes, heterochromatin is characterized by numerous epigenetic marks, including DNA methylation. Spreading of these marks into nearby active genes must be avoided in order to maintain appropriate gene expression. Here, we uncover Arabidopsis Methyl-CpG-Binding Domain 7 (MBD7) and Increased D...
ORGANISM(S): Arabidopsis thaliana 
Using MethylC-Seq to provide single-base resulution of DNA methylation status in ibm1-4 mutant 1 sample examined, ibm1-4 mutant
ORGANISM(S): Arabidopsis thaliana 
1, Using mRNA-Seq to get expression profiling of asi1-1 mutant and WT; 2, Using MethylC-Seq to provide single-base resulution of DNA methylation status in asi1-1 mutant mRNA-Seq: 2 samples examined, Col-0 wild-type with 35S-SUC2 transgene(termed as WT) and asi1-1 mutant (Col-0 background with 35S-SU...
ORGANISM(S): Arabidopsis thaliana 
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