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MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
UnknownEffectiveness of Xin Jia Xuan Bai Cheng Qi Decoction in treating acute exacerbation of chronic obstructive pulmonary disease: study protocol for a multicentre, randomised, controlled trial.
Not available
S-EPMC6924718 | biostudies-literature
MetabolomicsFoHsf1 reprograms central metabolism via caffeine and vitamin D2 to modulate development and virulence of Fusarium oxysporum on Polygonatum kingianum
Root rot has severely affected the yield and quality of Polygonatum kingianum, and Fusarium oxysporum has been identified as the primary causal agent. To explore the virulence mechanisms of this pathogen, we performed a functional characterization of FoHsf1, a gene encoding a heat shock transcriptio...
2026-04-11 | MTBLS14221 | MetaboLights
ProteomicsHuman Cell 293T BCAT1 IP GC-LC-MS
To identify the potential interaction protein that interacts with BCAT1 by IP-MS, we established the stable cell line with vector and BCAT1 in AGS. Then ten million cells were collected lysed in ice-cold 0.1% NP-40 buffer (50 mM Na2HPO4, pH 7.5, 150 mM NaCl) with protease inhibitors cocktail (Sigma,...
ORGANISM(S): Homo sapiens (Human) 
2024-11-15 | PXD041556 | Pride
Huamn bcat1 ip-ms 
MetabolomicsCombined analysis of cecal microbiota and metabolomics reveals the intervention mechanism of Dayuan Yin in acute lung injury

The ancient Chinese medicinal formula, Dayuan Yin (DYY), has a long history of use in treating respiratory ailments and shown to be effective in treating acute infectious diseases. This study aims to explore how DYY may impact intestinal flora and metabolites induced by acute lung injury (ALI). A...

2024-09-20 | MTBLS10741 | MetaboLights
UnknownDiameter Class-Dependent Species-Specific Tree-Soil Feedback Linked to Soil Quality Between <i>Cunninghamia lanceolata</i> (Lamb.) Hook. and <i>Quercus fabri</i> Hance in Subtropical Forests.
Not available
S-EPMC12899702 | biostudies-literature
ProteomicsE3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1
Atherosclerosis arises from disrupted cholesterol metabolism, notably impaired macrophage cholesterol efflux leading to foam cell formation. Through single-cell and bulk RNA sequencing, we identified Listerin as a regulator of macrophage cholesterol metabolism. Listerin expression increased during a...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-11 | PXD064538 | Pride
Ubiquitination modification cholesterol efflux foam cell atherosclerosi 
ProteomicsE3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1
Atherosclerosis arises from disrupted cholesterol metabolism, notably impaired macrophage cholesterol efflux leading to foam cell formation. Through single-cell and bulk RNA sequencing, we identified Listerin as a regulator of macrophage cholesterol metabolism. Listerin expression increased during a...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-11 | PXD064532 | Pride
Ubiquitination modification cholesterol efflux foam cell atherosclerosi 
UnknownQ allele overexpression and alternative splicing can improve wheat yield by increasing thousand-kernel weight and grain number per spike.
Not available
S-EPMC12910859 | biostudies-literature
ProteomicsA protein-centric glycoproteomic strategy identifies site-specific glycans as robust diagnostic markers for hepatocellular carcinoma
In this study, we achieved the quantitative glycoproteomics analysis of a large cohort of clinical specimens including 100 Hepatocellular carcinoma (HCC) and 100 healthy control human serums by using an integrated platform.
ORGANISM(S): Homo Sapiens (human) 
2026-06-26 | PXD065283 | JPOST Repository
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