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TranscriptomicsTranscriptome analysis of plaque and pWAT immune cells of 16 weeks fed high fat high cholesterol diet LXRa WT and S196A mice.
Purpose: The goals of this study is to evaluate the impact of LXRa phosphorylation at S196 in immune cells on atherosclerosi and obesity, on gene expression via RNA-seq. Lab Methods: Bone marrow from LXRa WT and S196A mice was transplanted into Ldlr-/- mice, which were fed a high fat, high cholester...
ORGANISM(S): Mus musculus 
2021-01-31 | GSE162660 | GEO
ProteomicsE3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1
Atherosclerosis arises from disrupted cholesterol metabolism, notably impaired macrophage cholesterol efflux leading to foam cell formation. Through single-cell and bulk RNA sequencing, we identified Listerin as a regulator of macrophage cholesterol metabolism. Listerin expression increased during a...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-11 | PXD064538 | Pride
Ubiquitination modification cholesterol efflux foam cell atherosclerosi 
ProteomicsE3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1
Atherosclerosis arises from disrupted cholesterol metabolism, notably impaired macrophage cholesterol efflux leading to foam cell formation. Through single-cell and bulk RNA sequencing, we identified Listerin as a regulator of macrophage cholesterol metabolism. Listerin expression increased during a...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-11 | PXD064532 | Pride
Ubiquitination modification cholesterol efflux foam cell atherosclerosi 
GenomicsTranscriptome analysis of plaque and pWAT immune cells of 16 weeks fed high fat high cholesterol diet LXRa WT and S196A mice.
Transcriptome analysis of plaque and pWAT immune cells of 16 weeks fed high fat high cholesterol diet LXRa WT and S196A mice.
PRJNA682586 | ENA
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