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ProteomicsREGγ is essential to maintain bone homeostasis by degrading TRAF6, preventing osteoporosis
Primary osteoporosis, manifesting as decreased bone mass and increased bone fragility, is a “silent disease” that is often ignored until a bone breaks. Accordingly, it is urgent to develop reliable biomarkers and novel therapeutic strategies for osteoporosis treatment. Here, we identified REGγ as...
ORGANISM(S): Homo Sapiens 
2024-10-27 | PXD057237 |
ProteomicsLiquid chromatography-mass spectrometry based tissue metabolic profiling reveals major metabolic pathway alterations and potential biomarkers of lung cancer
MS spectrum of lung tissue metabolic analysis in 131 patients with lung cancer or benign lung tumor. These include lung cancer tissues/benign tumor tissues, adjacent normal tissues and distal normal tissues.
ORGANISM(S): Cancer 
2020-06-19 | PXD019969 |
ProteomicsIntegrative Proteogenomic Characterization Reveals Therapeutic Targets in Poorly Differentiated and Anaplastic Thyroid Cancers
In our study, we constructed a multicenter thyroid-cancer cohort consisting of 467 formalin-fixed paraffin-embedded (FFPE) samples, among which WES, proteome, and phosphorylated proteome analysis were conducted. Thyroid tumors consisted of 124 ATC samples, 47 PDTC samples and 177 PTC samples (includ...
ORGANISM(S): Homo Sapiens 
2025-03-16 | PXD054521 |
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