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Tet-mediated DNA oxidation is a new type of epigenetic modification in mammals and its role in the regulation of cell fate transition remains poorly understood. Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three Tet genes and examine their capability to be reprogrammed into iPS ...
ORGANISM(S): Mus musculus 
In total, 5134 protein groups were identified, among which 4169 proteins were quantified. The fold-change cutoff was set when proteins with quantitative ratios above 1.3 or below 1/1.3 and P value<0.05 are deemed significant. Among the quantified proteins, 70 proteins are up-regulated and 104 protei...
ORGANISM(S): Elymus sibiricus 
2021-09-09 | PXD021552 | Pride
Small RNAs in plants are protected by 2'-O-methylation at 3' terminal nucleotide by HEN1. In hen1 mutant, small RNAs lacking 3' methylation are truncated and tailed at 3' end. We identified a nucleotidyltransferase gene HESO1 in Arabidopsis that tails small RNAs in hen1. In order to study the small ...
ORGANISM(S): Arabidopsis thaliana 
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