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TranscriptomicsDifferential gene expression between uninfected and infected U937 derived macrophages with  Leishmania braziliensis
The main objective of this study is to identify the list of genes differentially expressed between infected with Leishmania braziliensis and non-infected macrophage cultures based on gene expression microarray profiling The dataset is comprised by the expression profile of 6 samples from three inde...
ORGANISM(S): Homo sapiens 
2015-06-10 | E-GEOD-61211 | biostudies-arrayexpress
TranscriptomicsHuman transcriptome pattern of primary cutaneous lesions from patients with localized cutaneous leishmaniasis and mucosal leishmaniasis
We evaluated the trancriptome of primary cutaneous leisions caused by infection with Leishmania braziliensis. mRNA-seq technique was used to study the trancriptome of both host and parasite. A total of 10 samples was obtained from primary skin ulcers of two extreme clinical forms of American tegumen...
ORGANISM(S): Homo sapiens 
2012-10-24 | E-GEOD-33601 | biostudies-arrayexpress
ProteomicsLeishmania braziliensis Protein Arginine Methyltransferases interactomes
We functionally characterized the five predicted PRMTs in Leishmania braziliensis by gene knockout and endogenous protein HA tagging using CRISPR/Cas9 gene editing. We report that R-methylation profiles vary among Leishmania species and across L. braziliensis lifecycle stages, with the peak PRMT exp...
ORGANISM(S): Leishmania braziliensis 
2022-03-03 | PXD031057 | Pride
Leishmania braziliensis Prmt Protein arginine methyltransferase Gene knockout Crispr/cas9 
GenomicsLeishmania braziliensis
Leishmania braziliensis Genome sequencing and assembly
PRJNA292004 | ENA
GenomicsLeishmania braziliensis
Leishmania braziliensis Genome sequencing
PRJNA475480 | ENA
TranscriptomicsMicroRNAome comparison between macrophages infected with Leishmania RNA virus containing L.guyanensis and virus-free parasites
Leishmania RNA virus is an endosymbiotic virus of obligate intracellular Leishmania parasites. The presence of Leishmania RNA virus has been associated to metastatic leishmaniasis in hamsters and the failure of the first-line treatment in humans. This experiment aims to find the differences in the m...
ORGANISM(S): Mus musculus 
2016-09-01 | E-MTAB-4413 | biostudies-arrayexpress
GenomicsLeishmania braziliensis strain:M2903
Leishmania braziliensis siRNA sequencing
PRJNA176736 | ENA
ProteomicsCharacterization of differentially abundant proteins among Leishmania (Viannia) braziliensis strains isolated from atypical or typical lesions
Leishmania (Viannia) braziliensis is the main etiological agent of cutaneous and mucocutaneous leishmaniasis in Latin America. Reports have described non-ulcerated atypical tegumentary leishmaniasis cases caused by L. braziliensis in several regions of the world, including in patients from the Xacri...
ORGANISM(S): Leishmania braziliensis 
2022-02-11 | PXD029995 | Pride
Leishmania braziliensis Abundance Atypical Tmt. Label based Proteome 
GenomicsLeishmania braziliensis strain:M2903 | isolate:LbrM2903
Leishmania braziliensis strain:M2903 | isolate:LbrM2903 Transcriptome or Gene expression
PRJNA493750 | ENA
GenomicsLeishmania braziliensis strain:M2904
Leishmania braziliensis strain:M2904 Raw sequence reads
PRJNA299517 | ENA
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