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TranscriptomicsTranscription profiling of human U2OS-ERalpha cells induced with doxycycline reveals selective estrogen receptor-beta agonists repress transcription of proinflammatory genes
In addition to their role in the development and function of the reproductive system, estrogens have significant anti-inflammatory properties. Although both estrogen receptors (ERs) can mediate anti-inflammatory actions, ERbeta is a more desirable therapeutic target because ERalpha mediates the prol...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-11115 | biostudies-arrayexpress
TranscriptomicsGenome wide expression analysis of ER alpha and beta with or without E2 treatment in U2OS cell line.
Estrogen receptorï?  beta (ER beta) has potent anti-proliferative and anti-inflammatory properties, suggesting that ER beta-selective agonists might be a new class of therapeutic and chemopreventative agents. To understand how ER beta regulates genes, we identified genes regulated by the unliganded ...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-21769 | biostudies-arrayexpress
TranscriptomicsGenome wide analysis of ER beta in U2OS cells
This SuperSeries is composed of the following subset Series: GSE21769: Genome wide expression analysis of ER alpha and beta with or without E2 treatment in U2OS cell line. GSE21770: Genome-wide maps of ER beta binding sites in U2OS cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-05-11 | E-GEOD-21790 | biostudies-arrayexpress
GenomicsGenome-wide maps of ERbeta binding sites in U2OS cells
Estrogen receptor beta (ERbeta) has potent anti-proliferative and anti-inflammatory properties, suggesting that ER beta-selective agonists might be a new class of therapeutic and chemopreventative agents. To understand how ER beta regulates genes, we identified genes regulated by the unliganded and ...
ORGANISM(S): Homo sapiens 
2010-05-12 | E-GEOD-21770 | biostudies-arrayexpress
UnknownDifferential regulation of native estrogen receptor-regulatory elements by estradiol, tamoxifen, and raloxifene.
Not available
S-EPMC2234590 | biostudies-literature
UnknownGABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.
Not available
S-EPMC3410621 | biostudies-literature
UnknownEstrogen receptor beta binds to and regulates three distinct classes of target genes.
Not available
S-EPMC2903369 | biostudies-literature
UnknownImpact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa.
Not available
S-EPMC6467198 | biostudies-literature
UnknownEnhancement of conservation knowledge through increased access to botanical information.
Not available
S-EPMC6850347 | biostudies-literature
UnknownPharmacotherapy for Non-Cystic Fibrosis Bronchiectasis: Results From an NTM Info & Research Patient Survey and the Bronchiectasis and NTM Research Registry.
Not available
S-EPMC6026272 | biostudies-literature
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