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UnknownInterrogating ligand-receptor interactions using highly sensitive cellular biosensors.
Not available
S-EPMC10684770 | biostudies-literature
UnknownPeptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice.
Not available
S-EPMC6420116 | biostudies-literature
UnknownChoroidal thickness maps from spectral domain and swept source optical coherence tomography: algorithmic versus ground truth annotation.
Not available
S-EPMC5774332 | biostudies-literature
GenomicsGermline variants in the SEMA4A gene predispose to familial colorectal cancer type X
Familial colorectal cancer type X (FCCTX) is characterized by clinical features of hereditary non-polyposis colorectal cancer with a yet undefined genetic background. Here, using an integrative genomics strategy, we identify the SEMA4A p.Val78Met germline mutation in an Austrian kindred with FCCTX. ...
EGAS00001000957 | EGA
Genomicsena-DATASET-MUG-11-09-2014-07:42:30:338-15 - samples
Exome sequencing of peripheral blood from 4 individuals of a family with familial colorectal cancer type X
EGAD00001001009 | EGA
Genomicsena-DATASET-MUG-11-09-2014-07:45:47:901-16 - samples
Sequencing of colorectal tumors and normal tissue using Ion AmpliSeq Cancer Hotspot Panel V2
EGAD00001001010 | EGA
GenomicsDAC CTC - Plasma-DNA
Data Access Committee EGAC00001000072
EGAC00001000072 | EGA
TranscriptomicsContribution of the STAT1alpha and STAT1beta isoforms to IFN-gamma mediated innate immunity
The transcription factor STAT1 is essential for interferon- (IFN) mediated protective immunity in humans and mice. Two splice isoforms of STAT1, STAT1M-NM-1 and STAT1M-NM-2, differ with regard to a C-terminal transactivation domain, which is absent in STAT1M-NM-2. Dimers of STAT1M-NM-2 are therefore...
ORGANISM(S): Mus musculus 
2014-04-04 | E-GEOD-48970 | biostudies-arrayexpress
ProteomicsMolecular details of ligand binding to the intrinsically disordered N terminus of the neuropeptide Y receptor
Neuropeptide Y (NPY) receptors comprise a family of rhodopsin-like G-protein coupled receptors (GPCRs) that participate in controlling food intake, memory retention, and circadian rhythm, making them highly attractive drug targets. However, the multiligand nature of NPY receptors, such as the NPY re...
ORGANISM(S): Homo Sapiens Escherichia Coli Sus Scrofa 
2026-03-24 | PXD051865 | panorama
TranscriptomicsTranscriptional co-factor TBLR1 controls lipid mobilization in white adipose tissue
Lipid mobilization (lipolysis) in white adipose tissue (WAT) critically controls lipid turnover and adiposity in humans. While the acute regulation of lipolysis has been studied in detail, the transcriptional determinants of WAT lipolytic activity remain still largely unexplored. Here we show that ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-43658 | biostudies-arrayexpress
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