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ProteomicsA precisely positioned MED12 activation helix stimulates CDK8 kinase activity
Chemical cross-linking coupled to mass spectrometry was used to study binary and ternary complexes involving cyclin-dependent kinase 8 (CDK8), cyclin-C, and subunit 12 of the Mediator complex (MED12). Cross-linking was performed using different cross-linking chemistries: (1) disuccinimidyl suberate ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD015394 | Pride
Chemical cross-linking  dss  pdh  dmtmm  structural proteomics  mediator complex  kinase 
UnknownExogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity.
Not available
S-EPMC12592183 | biostudies-literature
UnknownThe Selection of a Hepatocyte Cell Line Susceptible to Plasmodium falciparum Sporozoite Invasion That Is Associated With Expression of Glypican-3.
Not available
S-EPMC6413710 | biostudies-literature
UnknownSerological profiles of pan-coronavirus-specific responses in COVID-19 patients using a multiplexed electro-chemiluminescence-based testing platform.
Not available
S-EPMC8174743 | biostudies-literature
UnknownComparison of major, minor and junctional circumsporozoite protein epitopes for malaria vaccine design.
Not available
S-EPMC12494720 | biostudies-literature
UnknownResults from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.
Not available
S-EPMC3582548 | biostudies-literature
ProteomicsEngineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo
To realize a carbon-neutral bioeconomy, the concept of electrobiocatalysis has been developed, in which CO2 is first chemically reduced to formate and subsequently assimilated by enzymatic cascades or engineered microbes. A key step in the assimilation of formate is its reduction into formaldehyde, ...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-03-22 | MSV000091532 | MassIVE
UnknownChronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity.
Not available
S-EPMC7190915 | biostudies-literature
UnknownRegulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist.
Not available
S-EPMC6152342 | biostudies-literature
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
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