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GenomicsA Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs (ChIP-Seq)
During limb development, Hoxd genes are transcribed in two waves: Early on, when the arm and forearm are specified and subsequently, when digits form. While the latter phase is controlled by enhancers centromeric to the HoxD cluster, we show here that the early phase requires enhancers located in th...
ORGANISM(S): Mus musculus 
2013-06-07 | E-GEOD-45456 | biostudies-arrayexpress
GenomicsThe Dynamic Architecture of Hox Gene Clusters
The spatial and temporal control of Hox gene transcription is essential for patterning the vertebrate body axis. Although this process involves changes in histone posttranslational modifications, the existence of particular three-dimensional (3D) architectures remained to be assessed in vivo. Using ...
ORGANISM(S): Mus musculus 
2011-10-12 | E-GEOD-31570 | biostudies-arrayexpress
TranscriptomicsHoxD locus
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-45242 | biostudies-arrayexpress
TranscriptomicsTranscriptome along the hedgehog developing gut
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Atelerix albiventris 
2013-10-23 | E-GEOD-44696 | biostudies-arrayexpress
TranscriptomicsTranscriptome in developing caeca
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44367 | biostudies-arrayexpress
TranscriptomicsTranscriptome along the murine developing gut
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44366 | biostudies-arrayexpress
TranscriptomicsSpatial organization of chromatin at the HoxD locus in developing caeca (4C-seq)
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44360 | biostudies-arrayexpress
TranscriptomicsSpatial organization of chromatin at the HoxD locus in developing caeca (4C tiling chip)
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44357 | biostudies-arrayexpress
TranscriptomicsTranscription landscape at the HoxD locus in developing caeca
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44362 | biostudies-arrayexpress
TranscriptomicsChromatin landscape at the HoxD locus in developing caeca (ChIP-chip)
Hox genes are required for the development of the intestinal caecum, a major organ of species eating plants. We have analysed the transcriptional regulation of Hoxd genes in caecal buds and show that they are controlled by a series of enhancers located in a gene desert telomeric to the HoxD cluster....
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44361 | biostudies-arrayexpress
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