Sort   by:  
 Page size 
GenomicsTCERG1 regulates alternative splicing of Bcl-x gene by modulating the rate of RNAPII transcription
Complex functional coupling exists between transcriptional elongation and pre-mRNA alternative splicing. Pausing sites and changes in the rate of transcription by RNAPII may therefore have a fundamental impact in the regulation of alternative splicing. Here, we show that the elongation and splicing-...
ORGANISM(S): Homo sapiens 
2012-01-12 | E-GEOD-33716 | biostudies-arrayexpress
TranscriptomicsA function for the hnRNP A1/A2 proteins in transcription elongation
The hnRNP A1 and A2 proteins regulate processes such as alternative pre-mRNA splicing and mRNA stability. Here, we report that a reduction in the levels of hnRNP A1 and A2 by RNA interference or their cytoplasmic retention by osmotic stress drastically increases the transcription of a reporter gene....
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-67617 | biostudies-arrayexpress
Sort   by:  
 Page size