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TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status [PK-ChIP]
Cohesin acetylation by Eco1 during DNA replication establishes sister chromatid cohesion. We show that acetylation makes cohesin resistant to Wapl activity from S-phase until mitosis. Wapl turns out to be a key regulator of cohesin dynamics on chromosomes by controling cohesin maintenance following ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42457 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status [BrdU-ChIP].
Cohesin acetylation by Eco1 during DNA replication establishes sister chromatid cohesion. We show that acetylation makes cohesin resistant to Wapl activity from S-phase until mitosis. Wapl turns out to be a key regulator of cohesin dynamics on chromosomes by controling cohesin maintenance following ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42456 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42460 | biostudies-arrayexpress
TranscriptomicsDistribution of different proteins related to sister chromatid cohesion during the cell cycle.
This series is a supplementary data set for the manuscript titled "Cohesin relocation from sites of chromosomal loading to places of convergent transcription" All data shown in the paper were registered (30 ChIP-chip and one transcription data). Experimental design: 1. Type of experiment: a. ChIP ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-09 | E-GEOD-1461 | biostudies-arrayexpress
TranscriptomicsHDACs act on ribosomal DNA to control the yeast replication program and the competition between origins for limiting initiation factors
In S. cerevisiae, replication timing is controlled by epigenetic mechanisms restricting the accessibility of origins to limiting initiation factors. About 30% of these origins are located within repetitive DNA sequences such as the ribosomal DNA (rDNA) array, but their regulation is poorly understoo...
ORGANISM(S): Saccharomyces cerevisiae W303 
2014-03-26 | E-GEOD-56171 | biostudies-arrayexpress
GenomicsHDACs act on ribosomal DNA to control the yeast replication program and the competition between origins for limiting initiation factors [ChIP-seq]
In S. cerevisiae, replication timing is controlled by epigenetic mechanisms restricting the accessibility of origins to limiting initiation factors. About 30% of these origins are located within repetitive DNA sequences such as the ribosomal DNA (rDNA) array, but their regulation is poorly understoo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-14 | E-GEOD-57617 | biostudies-arrayexpress
GenomicsHDACs act on ribosomal DNA to control the yeast replication program and the competition between origins for limiting initiation factors [Mnase-seq]
In S. cerevisiae, replication timing is controlled by epigenetic mechanisms restricting the accessibility of origins to limiting initiation factors. About 30% of these origins are located within repetitive DNA sequences such as the ribosomal DNA (rDNA) array, but their regulation is poorly understoo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-14 | E-GEOD-57618 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status [expression]
Cohesin acetylation by Eco1 during DNA replication establishes sister chromatid cohesion. We show that acetylation makes cohesin resistant to Wapl activity from S-phase until mitosis. Wapl turns out to be a key regulator of cohesin dynamics on chromosomes by controling cohesin maintenance following ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42458 | biostudies-arrayexpress
TranscriptomicsEssential Roles of the Smc5/6 complex in Replication through Pausing Sites and Endogenous DNA Damage Tolerance
The essential functions of the conserved Smc5/6 complex remain elusive. To uncover its roles in genome maintenance, we established Saccharomyces cerevisiae cell cycle-regulated alleles that enable restriction of Smc5/6 components to S or G2/M. Unexpectedly, the essential functions of Smc5/6 segregat...
ORGANISM(S): Saccharomyces cerevisiae 
2015-11-19 | E-GEOD-72241 | biostudies-arrayexpress
TranscriptomicsCohesin association to replication sites depends on Rad50 and promotes fork restart
The cohesin complex holds together newly-replicated chromatids and is involved in diverse pathways that preserve genome integrity. We show that in budding yeast, cohesin is transiently recruited to active replication origins and it spreads along DNA as forks progress. When DNA synthesis is impeded, ...
ORGANISM(S): Saccharomyces cerevisiae W303 
2012-10-01 | E-GEOD-39078 | biostudies-arrayexpress
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