Sort   by:  
 Page size 
TranscriptomicsPTEN loss deM-oM-,M-^Anes a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) represents a heterogeneous diagnostic category with distinct molecular subtypes that can be deM-oM-,M-^Aned by gene expression proM-oM-,M-^Aling. However, even within these deM-oM-,M-^Aned subtypes, heterogeneity prevails. To further elucidate the pathogenesis o...
ORGANISM(S): Homo sapiens 
2013-07-09 | E-GEOD-45495 | biostudies-arrayexpress
TranscriptomicsMCL1 is deregulated in subgroups of diffuse large B-cell lymphoma
MCL1 is an anti-apoptotic member of the BCL2 family that is deregulated in various solid and hematological malignancies. However, its role in the molecular pathogenesis of diffuse large B-cell lymphoma (DLBCL) is unclear. We analyzed gene expression profiling data from 350 DLBCL patient samples and ...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-43272 | biostudies-arrayexpress
TranscriptomicsEssential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma survival
Three ALCL cell lines DEL, FEPD and K299 were induced with an IRF4-specific shRNA for up to 96 hours. The three ALCL cell lines DEL, FEPD and K299 were induced with an IRF4-specific shRNA for four durations and compared with the corresponding not-induced control.
ORGANISM(S): Homo sapiens 
2015-01-03 | E-GEOD-59747 | biostudies-arrayexpress
TranscriptomicsGEP of PMBCs during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer (RCC) patients
Tumor-induced immunosuppression remains a major challenge for immunotherapy of cancer patients. To further elucidate why an allogeneic gene-modified (Interleukin-7(IL-7)/CD80 co-transfected) renal cell cancer vaccine failed to induce clinically relevant TH1-polarized immune responses, peripheral blo...
ORGANISM(S): Homo sapiens 
2014-09-24 | E-GEOD-51490 | biostudies-arrayexpress
TranscriptomicsInduced pluripotent stem cells can be generated in bulk culture
Induced pluripotent stem cells (iPSCs) are usually clonally derived. The selection of fully reprogrammed cells generally involves picking of individual colonies with morphology similar to embryonic stem cells (ESCs). However, successfully reprogrammed cells are highly proliferative and escape from c...
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-42807 | biostudies-arrayexpress
TranscriptomicsIkB-like protein NFKBIZ regulates NF-kB signaling and is critical for survival of ABC DLBCL (MLN inhibition)
Constitutive activation of the nuclear factor-kappa B (NF-kB) pathway is a hallmark of the activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL). Recurrent mutations of NF-kB regulators that cause constitutive activity of this oncogenic pathway have been identified. However, i...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-46972 | biostudies-arrayexpress
TranscriptomicsTissue- and Aging-specific DNA-Methylation Patterns are erased in Mesenchymal Stromal Cells derived from Induced Pluripotent Stem Cells. [Methylation profiling]
Standardization of mesenchymal stromal cells (MSCs) remains a major obstacle in regenerative medicine. Starting material and culture expansion affect cell preparations and render comparison between studies difficult. In contrast, induced pluripotent stem cells (iPSCs) assimilate towards a ground-sta...
ORGANISM(S): Homo sapiens 
2014-09-24 | E-GEOD-54767 | biostudies-arrayexpress
UnknownPan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes.
Not available
S-EPMC7952699 | biostudies-literature
TranscriptomicsExpression data from treatment-induced senescence in mouse Emu-myc B-cell lymphoma model
Treatment induced senescence (TIS) is a terminal cell cycle arrest program, increasingly recognized as a tumor suppressor mechanism complementing apoptosis in response to standard chemotherapy regimens. In particular cells with blocked apoptotic pathways rely on senescence as the only remaining fail...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-31099 | biostudies-arrayexpress
UnknownGenomic selection for resistance to spruce budworm in white spruce and relationships with growth and wood quality traits.
Not available
S-EPMC7691460 | biostudies-literature
Sort   by:  
 Page size