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TranscriptomicsHDAC1/2 and CD4+ T cells
Dynamic changes in histone acetylation patterns are mediated by the activity of histone acetyltransfereases (HATs) and histone deacetylases (HDACs) and are key events in the epigenetic regulation of gene expression. The application of HDAC inhibitors revealed a variety of T cell functions controlled...
ORGANISM(S): Mus musculus 
2014-03-30 | E-MTAB-2184 | biostudies-arrayexpress
UnknownParachironomus lenz from china and Japan (Diptera, chironomidae).
Not available
S-EPMC4400376 | biostudies-literature
ProteomicsThe Golgi stacking protein GRASP55 is targeted by the natural compound prodigiosin
The bacterial secondary metabolite prodigiosin has been shown to exert anticancer, antimalarial, antibacterial and immunomodulatory properties. With regard to cancer, it has been reported to affect cancer cells but not non-malignant cells, rendering prodigiosin a promising lead compound for anticanc...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD043247 | Pride
Prodigiosin  golgi apparatus  natural compound  autophagy  target identification 
UnknownBCOR analysis in patients with OFCD and Lenz microphthalmia syndromes, mental retardation with ocular anomalies, and cardiac laterality defects.
Not available
S-EPMC2826145 | biostudies-literature
Unknownt-Darpp Activates IGF-1R Signaling to Regulate Glucose Metabolism in Trastuzumab-Resistant Breast Cancer Cells.
Not available
S-EPMC7007690 | biostudies-literature
ProteomicsThermal Proteome Profiling Datasets for smarTPCA
Chemical biology and the application of small molecules has proven to be a potent perturbation strategy especially for the functional elucidation of proteins, their networks and regulators. In recent years, the cellular thermal shift assay (CETSA) and its proteome-wide extension, thermal proteome pr...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD032942 | Pride
Kinase inhibitors Small molecule arranged thermal proximity coaggregation (smartpca) Tpp with temperature range (tpp-tr) or compound concentration range (tpp-ccr) Hl-60 cell line Thermal proteome profiling (tpp) 
UnknownLenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions.
Not available
S-EPMC4843478 | biostudies-literature
UnknownClinical development of CAR T cells-challenges and opportunities in translating innovative treatment concepts.
Not available
S-EPMC5582407 | biostudies-literature
UnknownCD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells.
Not available
S-EPMC6594241 | biostudies-literature
UnknownA T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Not available
S-EPMC6320368 | biostudies-literature
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