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ProteomicsThe Golgi stacking protein GRASP55 is targeted by the natural compound prodigiosin
The bacterial secondary metabolite prodigiosin has been shown to exert anticancer, antimalarial, antibacterial and immunomodulatory properties. With regard to cancer, it has been reported to affect cancer cells but not non-malignant cells, rendering prodigiosin a promising lead compound for anticanc...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD043247 | Pride
Prodigiosin  golgi apparatus  natural compound  autophagy  target identification 
ProteomicsThe Golgi stacking protein GRASP55 represents an effector protein of the natural compound Prodigiosin
The bacterial secondary metabolite prodigiosin has been shown to exert anticancer, antimalarial, antibacterial and immunomodulatory properties. With regard to cancer, it has been reported that it affects tumor cells but not non-malignant cells, making it a promising lead compound for anticancer drug...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042909 | Pride
Prodigiosin  golgi apparatus  natural compound  autophagy  target identification  secretome 
TranscriptomicsInsight into the regulation of prodigiosin production by temperature in Serratia marcescens through transcriptome analysis
We report the application of transcriptome sequencing technology for high-throughput profiling of Serratia marcescens for producing prodigiosin. By obtaining over 163 million bases of sequence from Serratia marcescens genome DNA, we generated transcriptome -state maps of Serratia marcescens 12h cell...
ORGANISM(S): Serratia marcescens 
2020-12-31 | GSE144646 | GEO
GenomicsInsight into the regulation of prodigiosin production by temperature in Serratia marcescens through transcriptome analysis
Insight into the regulation of prodigiosin production by temperature in Serratia marcescens through transcriptome analysis
PRJNA604408 | ENA
UnknownSelective Cytotoxic Activity of Prodigiosin@halloysite Nanoformulation.
Not available
S-EPMC7264093 | biostudies-literature
UnknownProdigiosin Induces Autolysins in Actively Grown Bacillus subtilis Cells.
Not available
S-EPMC4729933 | biostudies-literature
GenomicsAmbigols from the Cyanobacterium Fischerella ambigua increase Prodigiosin Production in Serratia sp.
Ambigols from the Cyanobacterium Fischerella ambigua increase Prodigiosin Production in Serratia sp.
PRJNA635824 | ENA
UnknownTranscriptional factor OmpR positively regulates prodigiosin biosynthesis in Serratia marcescens FZSF02 by binding with the promoter of the prodigiosin cluster.
Not available
S-EPMC9712742 | biostudies-literature
UnknownTranscriptomic analysis of the antimicrobial activity of prodigiosin against Cutibacterium acnes.
Not available
S-EPMC10576067 | biostudies-literature
TranscriptomicsAmbigols from the Cyanobacterium Fischerella ambigua increase Prodigiosin Production in Serratia sp.
Screening a library of 573 cyanobacteria extracts for inhibition of the quorum sensing regulated prodigiosin production of Serratia marcescens, an extract of the cyanobacterium Fischerella ambigua (Näg.) Gomont 108b was found to drastically increase the prodigiosin production. Bioactivity-guided iso...
ORGANISM(S): Prodigiosinella confusarubida 
2020-10-31 | GSE151437 | GEO
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