Sort   by:  
 Page size 
TranscriptomicsA new gene expression signature, the ClinicoMolecular Triad Classification, may improve prediction and prognostication of breast cancer at the time of diagnosis
When making treatment decisions, oncologists often stratify breast cancers into a low-risk group (ER+, low grade); an intermediate-risk group (ER+, high grade); and a high-risk group that includes Her2+ and triple-negative (ER-/PR-/Her2-) tumors. None of the currently available gene signatures corre...
ORGANISM(S): Homo sapiens 
2011-09-28 | E-GEOD-16987 | biostudies-arrayexpress
TranscriptomicsThe effects of timing of fine needle aspiration biopsies on gene expression profiles in breast cancers
Paired fine needle aspiration biopsies (FNABs) of breast cancers were taken before (PRE) and after (POST) surgeries from 16 patients and compared the cDNA microarray data to determine the genes that were differentially expressed between the FNABs taken at the two time points. The timing of fine need...
ORGANISM(S): Homo sapiens 
2008-09-09 | E-GEOD-12072 | biostudies-arrayexpress
TranscriptomicsSockeye salmon (Oncorhynchus nerka) from Aniakchak National Monument and Preserve muscle transcriptome
This dataset was gene expression from natural sockeye salmon populations used to test the preservation of coexpression networks that were found in lake whitefish. Here is the abstract of the manuscript:BackgroundM-BM- : A functional understanding of processes involved in adaptive divergence is one o...
ORGANISM(S): Oncorhynchus nerka 
2013-02-01 | E-GEOD-42985 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of MDA-MB-468 cells following p53-R273H mutant knock-down
A total of 58 genes were up-regulated (> 1.5 fold-change) while 117 genes were down-regulated Microarray experiments were performed in duplicate as follows: MDA-MB-468 cells were transduced with lentiviral shRNA targeting endogenous p53-R273H mutant (p53si-1)or a non-targeting shRNA (NS). Total RNA ...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-65967 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of MCF-7 cells treated with 6-shogaol
A total of 18 genes were up-regulated and 11 genes were down-regulated > 2-fold following 6-shogaol treatment Microarray experiments were performed in duplicate as follows: MCF-7 cells were treated with 10 uM of 6-shogaol or control vehicle (0.1% DMSO) for 48 h. Total RNA from cells was extracted us...
ORGANISM(S): Homo sapiens 
2012-09-01 | E-GEOD-36973 | biostudies-arrayexpress
TranscriptomicsHypoxia-induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling
Hypoxia (low oxygen) and Notch signaling are two important regulators of vascular development, but how they interact in controlling the choice between arterial and venous fates for endothelial cells during vasculogenesis is less well understood. In this report, we show that hypoxia and Notch signali...
ORGANISM(S): Mus musculus 
2013-02-08 | E-GEOD-35894 | biostudies-arrayexpress
TranscriptomicsThe effect on gene expression of Smchd1 deletion in primary MEFs, transformed MEFs and MEF tumours
Smchd1 appears to act as a tumour suppressor in the transformed fibroblast model. We find gene expression differences are most pronounced in the transformed MEFs. We always detect a small number of clustered genes and imprinted genes as differentially expressed, along with others involved in tumorig...
ORGANISM(S): Mus musculus 
2012-09-30 | E-GEOD-40734 | biostudies-arrayexpress
UnknownNTX250: A Modular mRNA-Based Immunotherapy Platform for HPV-Associated Cancers with Broad Applicability.
Not available
S-EPMC12485786 | biostudies-literature
TranscriptomicsStem-like glioma-propagating cells contribute to molecular heterogeneity and survival outcome in oligodendroglial tumors
Brain tumors are among the most malignant cancers and can arise from neural stem cells or oligodendrocyte progenitor cells (OPCs). Glioma-propagating cells (GPCs) that have stem-like properties have been derived from tumor variants such as glioblastoma multiforme (GBM) and oligodendroglial tumors, t...
ORGANISM(S): Homo sapiens 
2012-06-02 | E-GEOD-31545 | biostudies-arrayexpress
TranscriptomicsThe effect on gene expression of Smchd1 deletion in end stage lymphomas
Smchd1 appears to act as a tumour suppressor in the Eµ-Myc B cell lymphoma model. We find gene expression differences are most pronounced in the premalignant cells, and observe more variability in end stage lymphomas. We always detect a small number of clustered genes and imprinted genes as differen...
ORGANISM(S): Mus musculus 
2012-09-30 | E-GEOD-40880 | biostudies-arrayexpress
Sort   by:  
 Page size