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Background. Leptospirosis is among the most widespread zoonoses worldwide. Severe pulmonary hemorrhagic syndrome (SPHS) represents a serious complication of leptospirosis, with poor understanding of its underlying mechanisms and an urgent need for identification of effective biomarkers. Methods. A n...
ORGANISM(S): Homo sapiens (Human) Leptospira 
2026-02-09 | PXD052319 | Pride
Leptospirosis, an emerging zoonotic disease with worldwide distribution, is caused by spirochetes belonging to the genus Leptospira. More than 500,000 cases of severe leptospirosis are reported annually, with .10% of these being fatal. Leptospires can survive for weeks in suitably moist conditions b...
ORGANISM(S): Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 
Gene expression profiling of whole blood in patients with severe leptospirosis
Whole blood transcriptional profiling of Brazilian patients with acute leptospirosis to identify mechanisms associated with case fatality
ORGANISM(S): Homo sapiens 
2016-09-23 | GSE72946 | GEO
Background: Leptospirosis is a global zoonotic infectious disease with various clinical manifestations ranging from mild self-limiting illness to life-threatening infection with multi-organ damage. This study was aimed at investigating transcription profiles from whole blood samples of patients with...
ORGANISM(S): Homo sapiens 
2025-04-01 | GSE200188 | GEO
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