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TranscriptomicsR. conorii transcriptional response within inoculation eschar battlefield
Rickettsia conorii, the causative agent of the MSF is transmitted to humans by the bite of infected ticks Rhipicephalus sanguineus. The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within...
ORGANISM(S): Rickettsia conorii 
2008-11-06 | E-GEOD-12130 | biostudies-arrayexpress
TranscriptomicsGenotyping of Coxiella burnetii strains collection
Genotyping based on genomic comparative hybridization of different isolates of coxiella burnetii compared to NMI reference strain Two-condition experiment, NMI vs. isolates. One replicate per isolate.
ORGANISM(S): Coxiella burnetii 
2011-12-31 | E-GEOD-31543 | biostudies-arrayexpress
TranscriptomicsMultiomics study to identify virulence factors of Rickettsia prowazekii revealed its adaptive mutation capabilities
We identified four virulence phenotypes of Rickettsia prowazekii (the deadly agent of epidemic typhus) that are associated with the upregulation of antiapoptotic genes (virulent strain) or the Interferon I pathway (avirulent). Transcriptional and proteomic analyses of R. prowazekii linked surface pr...
ORGANISM(S): Rickettsia prowazekii 
2010-06-05 | E-GEOD-15630 | biostudies-arrayexpress
TranscriptomicsEarly response of Coxiella burnetii to temperature stress
Transcriptional profiling of Coxiella burnetii phase I (RSA 493) submitting either to Cold and Heat shock comparing to control untreated Coxiella burnetii phase I (RSA 493) grown at 35°C. Four experiments : Cold shock 30 min Vs 35°C; Cold shock 60 min Vs 35°C; Heat shock 30 min Vs 35°C; Heat sho...
ORGANISM(S): Coxiella burnetii 
2011-01-01 | E-GEOD-21778 | biostudies-arrayexpress
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