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TranscriptomicsGenome-wide microRNA expression analysis of clear cell Renal Cell Carcinoma by next generation deep sequencing
MicroRNAs (miRNAs), non-coding RNAs regulating gene expression, are frequently aberrantly expressed in human cancers. Next-generation deep sequencing technology enables genome-wide expression profiling of known miRNAs and discovery of novel miRNAs at unprecedented quantitative and qualitative accura...
ORGANISM(S): Homo sapiens 
2012-06-21 | E-GEOD-37616 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of fresh frozen clear-cell renal cell carcinoma tissues treated with VEGFR-TKIs in first line
Transcriptomic analysis using qRT-PCR was performed on fresh frozen clear-cell renal cell carcinoma tissues treated with VEGFR-TKIs in first line (n=109). The transcriptomic data from this experiment were analyzed together with miRNA sequencing data from FFPE samples from the same tumor (E-MTAB-1058...
ORGANISM(S): Homo sapiens 
2021-06-07 | E-MTAB-10592 | biostudies-arrayexpress
TranscriptomicsLocal regulation and clinical impact of complement gene expression in deceased and living donor kidney allografts
The biopsy samples obtained at implantation segregated in 2 distinct groups according to donor origin, with a cluster of 319 unique identified genes higher expressed in DD compared to LD kidneys, and 329 genes lower expressed (false discovery rate <5%). Using pathway analysis software a significant ...
ORGANISM(S): Homo sapiens 
2008-04-16 | E-GEOD-11166 | biostudies-arrayexpress
TranscriptomicsBIOMARGIN study: Gene expression profiling in patients with a kidney transplantation
Microarrays were used to analyze the gene expression in peripheral blood and kidney allograft biopsies from patients with a kidney transplantation to get more insight in the molecular mechanisms underlying the different clinical phenotypes of kidney transplant rejection. 117 peripheral blood samples...
ORGANISM(S): Homo sapiens 
2019-08-15 | E-GEOD-129166 | biostudies-arrayexpress
GenomicsKUL-MEL Laboratory of Molecular Endocrinology, KU Leuven
Data Access Committee EGAC00001000260
EGAC00001000260 | EGA
Genomicsena-DATASET-KU-MEL-12-04-2016-11:46:48:538-274 - samples
Exome sequencing of high-risk prostate cancer
EGAD00001002009 | EGA
Genomicsena-DATASET-KU-MEL-12-04-2016-11:49:00:586-275 - samples
high-throughput sequencing of methylated and hydroxymethylated DNA from tumor and non-tumor tissue of patients with high-risk prostate cancer
EGAD00001002010 | EGA
GenomicsExomes of High-risk Prostate cancer
DNA extracted from tumoral tissue of 39 patients was used for exome sequencing. As a comparison, DNA extracted from blood was used as a non-tumoral control. DNA was captured using the EZ SeqCap v3 exome kit from Roche and sequenced using an Illumina HiSeq instrument.
EGAS00001001015 | EGA
Genomics(h)MeDIP-Seq of high-risk prostate cancer
Immunoprecipitation of methylated and hydroxymethylated DNA was performed on DNA isolated from tumoral and non-tumoral prostate tissue of patients with high-risk disease. Samples were sequenced on the Illumina HiSeq as 50 bp single end.
EGAS00001001019 | EGA
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