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TranscriptomicsAffy Sjogren
Retuximab response transcription profiling in salivary glands from Sjogren patients
ORGANISM(S): Homo sapiens 
2010-01-05 | E-MEXP-1883 | biostudies-arrayexpress
TranscriptomicsTranscriptional correlates of FOXP3 expression in suppressive and non-suppressive primary human Treg cell clones.
Analysis of the transcriptional correlates of FOXP3 expression in suppressive and non-suppressive primary human Treg cell clones. Individual CD4+CD25High or Cd4+CD25- T cells were isolated from human PBMCs and expanded in vitro. After 3 weeks of expansion, individual clones were analysed for FOXP3 e...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-65650 | biostudies-arrayexpress
OtherA combined omics approach to generate the surface atlas of human naive CD4+ T cells during early TCR activation.
Data from ProteomeXchange, PXD ID: PXD001432. File: SUK5557A8MA2__008-Spender2_3hP SUK5557A8MA2-40-215297.mzml. Published as part of . From the Abstract: {{i}} ... Periodate oxidation and aniline-catalyzed oxime ligation (PAL) technology was applied with subsequent quantitative LC-MS/MS (PAL-qLC-MS...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310020145 | GPMDB
Resource Reanalysis 
TranscriptomicsscRNAseq of immune cells of patients with chronic graft-versus-host disease
In this study, we investigated somatic mutations in T cells in patients with various hematological disorders. To analyze immune cell phenotypes with somatic mutations, we performed scRNA+TCRab sequencing from 9 patients with chronic GVHD and clonal expansions of CD4+ or CD8+ T cells based on T cell ...
ORGANISM(S): Homo sapiens 
2024-04-10 | E-MTAB-13419 | biostudies-arrayexpress
MetabolomicsAn untargeted metabolomics approach to characterize short-term and long-term metabolic changes after bariatric surgery
Bariatric surgery is currently one of the most effective treatments for obesity and leads to significant weight reduction, improved cardiovascular risk factors and overall survival in treated patients. To date, most studies focused on short-term effects of bariatric surgery on the metabolic profile ...
2015-09-15 | MTBLS218 | MetaboLights
GenomicsCD20+ T cells in Monoclonal B Cell Lymphocytosis and Chronic Lymphocytic Leukemia
Quantification and phenotypic analysis of CD20+ T cells in MBL and CLL, and evaluation of the correlation of these phenotypic characteristics with disease features, particularly analysis of mutations in the TP53 gene from pathological B cells.
ORGANISM(S): Homo Sapiens 
2024-03-01 | PRJEB73349 | EVA
MetabolomicsFrom grape berries to wines: drought impacts on key secondary metabolites

AIM: We aimed to study the impact of water deficit on the concentration of key flavour and phenolic secondary metabolites of wines.

METHODS AND RESULTS: A drought-stress field trial was conducted on Vitis vinifera cv. Merlot and Tocai Friulano for two seaso...

2021-08-13 | MTBLS2330 | MetaboLights
TranscriptomicsTranscription Start Site (TSS) mapping and total RNAseq of Streptomyces scabies wild-type (WT) versus Streptomyces scabies ΔbtmL
The aim of this experiment was to map the transcription start sites (TSSs) in the bottromycin biosynthetic gene cluster from Streptomyces scabies, qualitatively assess the expression levels of this cluster within the bacterium's transcriptome and evaluate whether deletion of a potential regulatory g...
ORGANISM(S): Streptomyces scabiei 
2020-02-19 | E-MTAB-8236 | biostudies-arrayexpress
TranscriptomicsExpression profiling of ProB and PreB cells in Ebf1 heterozygous mouse bone marrow
Loss of one allele of Ebf1 impairs pre-B cell (B220+CD19+CD43low/negIgM-) expansion. In order to better understand the underlying cause of the reduced pre-B cell compartment in Ebf1+/- mice, we sorted pro-B (B220+CD19+CD43highIgM- ) as well as pre-B cells from Wt and Ebf1 heterozygote mutant mice an...
ORGANISM(S): Mus musculus 
2013-10-18 | E-GEOD-51385 | biostudies-arrayexpress
MetabolomicsSelective profiling of translationally active tRNAs and their dynamics under stress

During translation, transfer RNAs (tRNAs) deliver specific amino acids to the ribosome in a coordinated manner with the sequence encoded by the mRNA. Despite their central role in protein synthesis, the precise contribution of tRNAs to the modulation of translation remains poorly understood, prim...

2026-06-25 | MTBLS12806 | MetaboLights
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