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TranscriptomicsEpidermal cells help coordinate leukocyte migration during inflammation through fatty acid-fueled matrix metalloproteinase production
In addition to satisfying the metabolic demands of cells, mitochondrial metabolism helps regulate immune cell function. To date, such cell-intrinsic metabolic-immunologic cross-talk has only been described operating in cells of the immune system. Here we show that epidermal cells utilize fatty acid ...
ORGANISM(S): Danio rerio 
2014-04-01 | E-GEOD-56365 | biostudies-arrayexpress
UnknownAging modulates homeostatic leukocyte trafficking to the peritoneal cavity in a sex-specific manner.
Not available
S-EPMC10533226 | biostudies-literature
UnknownLoss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking.
Not available
S-EPMC9134083 | biostudies-literature
TranscriptomicsTranscription profiling of human lymphatic endothelial cells, mouse dermal cells and human skin cells reveals an inflammation-induced mechanism for leukocyte transmigration of lymphatic vessel endothelium.
The exit of antigen-presenting cells (APC) and lymphocytes from inflamed skin to afferent lymph is vital for the initiation and maintenance of dermal immune responses. How such exit is achieved and how cells transmigrate the distinct endothelium of lymphatic vessels is however unknown. Here we show ...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-6257 | biostudies-arrayexpress
GenomicsRapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome
Rapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome
PRJNA1219625 | ENA
UnknownTwo-photon microscopy analysis of leukocyte trafficking and motility.
Not available
S-EPMC2937149 | biostudies-literature
TranscriptomicsTpl2 promotes chemokine/chemokine receptor expression and macrophage migration during acute inflammation
In autoimmune diseases, accumulation of activated leukocytes correlates with inflammation and disease progression, and therefore, disruption of leukocyte trafficking is an active area of research. The protein kinase Tpl2 (MAP3K8) regulates leukocyte inflammatory responses and is also being investig...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-48338 | biostudies-arrayexpress
UnknownRejuvenation of leukocyte trafficking in aged mice through PEPITEM intervention.
Not available
S-EPMC11258258 | biostudies-literature
UnknownMicrofluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions.
Not available
S-EPMC3528552 | biostudies-literature
UnknownPEPITEM modulates leukocyte trafficking to reduce obesity-induced inflammation.
Not available
S-EPMC10081110 | biostudies-literature
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