Sort   by:  
 Page size 
UnknownIntimate partner sexual aggression against Chinese women: a mixed methods study.
Not available
S-EPMC4039065 | biostudies-literature
TranscriptomicsRNA-seq analysis of TCEAL1 knock down with/without docetaxel treatment to enhance docetaxel efficacy in prostate cancer
Docetaxel chemotherapy in metastatic prostate cancer offers only a modest survival benefit due to emerging resistance. This experiment studies effect of TCEAL1 gene knock down with/without docetaxel treatment. The TCEAL1 gene was identified as the top candidate gene in vivo CRISPR/Cas9 screen.
ORGANISM(S): Homo sapiens 
2020-10-07 | E-MTAB-9484 | biostudies-arrayexpress
GenomicsIn vivo CRISPR/Cas9 screen to identify candidate therapeutic gene targets to enhance docetaxel efficacy in prostate cancer
Docetaxel chemotherapy in metastatic prostate cancer offers only a modest survival benefit due to emerging resistance. To identify candidate therapeutic gene targets, we applied a murine prostate cancer orthograft model that recapitulates clinical invasive prostate cancer in a genome-wide CRISPR/Cas...
ORGANISM(S): Mus musculus 
2020-10-07 | E-MTAB-9482 | biostudies-arrayexpress
TranscriptomicsHistone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat
In Saccharomyces cerevisiae, ubiquitylation of histone H2B signals methylation of histone H3 at lysine residues 4 (K4) and 79. These modifications occur at active genes but are believed to stabilize silent chromatin by limiting movement of silencing proteins away from heterochromatin domains. In the...
ORGANISM(S): Saccharomyces cerevisiae 
2011-12-02 | E-GEOD-27934 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung cancer cells treated with 5-aza - a genome-wide screen for hypermethylated genes in lung cancer
Abstract; Background: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The “rules” governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are init...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5816 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies
BACKGROUND: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The "rules" governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are initially establishe...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6695 | biostudies-arrayexpress
UnknownUndergraduate research. Genomics Education Partnership.
Not available
S-EPMC2953277 | biostudies-literature
UnknownRobust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
Not available
S-EPMC2492393 | biostudies-literature
UnknownThe genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions.
Not available
S-EPMC2830162 | biostudies-literature
UnknownFacilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience.
Not available
S-EPMC7048401 | biostudies-literature
Sort   by:  
 Page size