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TranscriptomicsExtensive demethylation of repetitive elements during seed development underlies gene imprinting
DNA methylation is an epigenetic mark associated with transposable element silencing and gene imprinting in flowering plants and mammals. In plants, imprinting occurs in the endosperm, which nourishes the embryo during seed development. We have profiled Arabidopsis DNA methylation genome-wide in the...
ORGANISM(S): Arabidopsis thaliana 
2009-06-12 | E-GEOD-14570 | biostudies-arrayexpress
TranscriptomicsEccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways
Full title: Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. Unaccustomed eccentric exercise damages muscle tissue stimulating mechanisms of recovery and remodeling that may be affected by cellular protection by the sex...
ORGANISM(S): Homo sapiens 
2009-12-16 | E-GEOD-19062 | biostudies-arrayexpress
TranscriptomicsFoie WTS vs WT
Transcriptional and polysomal analysis of mice liver hepatocytes after 4-hour refeeding as compared to overnight starved controls.
ORGANISM(S): Mus musculus 
2013-01-24 | E-MEXP-3522 | biostudies-arrayexpress
TranscriptomicsEliane_IL2.Rapa bis
Administration of low-dose IL-2 prevents and cures type 1 diabetes (T1D) in NOD mice by boosting pancreatic regulatory T cells (Tregs) and is currently being evaluated in humans. Here, to improve treatment efficacy we tested higher IL-2 doses that, despite further boosting Tregs, rapidly precipitate...
ORGANISM(S): Mus musculus 
2013-12-10 | E-MEXP-3789 | biostudies-arrayexpress
TranscriptomicsS6K_RiBi
Transcriptional analysis of concequent lack of rpS6 kinase activity in mice livers hepatocytes due to deletion of S6 kinases 1 and 2 (S6K1 and S6K2).
ORGANISM(S): Mus musculus 
2013-01-16 | E-MEXP-3518 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human first and thrid trimester placenta and whole blood
Fifteen DNA methylation array experiments were performed on five human chromosome specific array platforms (NimbleGen: HG18_CHR13_FT, HG18_CHR18_FT, HG18_CHR21_FT, HG18_CHRX_FT, HG18_CHRY_FT), comparing: (1) one female whole blood immunoprecipitated DNA fragments to their input DNA, (2) one 1st tri...
ORGANISM(S): Homo sapiens 
2009-05-01 | E-TABM-507 | biostudies-arrayexpress
TranscriptomicssiRNA profiling of human synovial fibroblasts depleted for clusterin
Analysis of synoviocytes cell form patients suffering of Rheumatoid arthritis and depleted for clusterin by siRNA knockdown. Note: this experiment was reloaded into ArrayExpress on 2nd December 2009 because the incorrect array design had originally been selected. The identifiers in the datafile wer...
ORGANISM(S): Homo sapiens 
2009-12-04 | E-TABM-653 | biostudies-arrayexpress
TranscriptomicsHistone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
Eukaryotic chromatin is separated into functional domains differentiated by posttranslational histone modifications, histone variants, and DNA methylation. Methylation is associated with repression of transcriptional initiation in plants and animals, and is frequently found in transposable elements...
ORGANISM(S): Arabidopsis thaliana 
2008-10-02 | E-GEOD-12212 | biostudies-arrayexpress
UnknownHealth financing policies during the COVID-19 pandemic and implications for universal health care: a case study of 15 countries.
Not available
S-EPMC10664823 | biostudies-literature
TranscriptomicsTranscription profiling by array of mouse CD4+ GFP+ (tregs) and CD4+ GFP- (Teffs) cells treated with IL-2
To obtain the molecular signature of the effect that the IL-2 therapeutic dose induces on T cells in vivo, we performed gene array analysis. Since it was critical to perform this analysis on highly purified Tregs and Teffs, and also because activated Teffs can acquire CD25 expression, we used GFP-Fo...
ORGANISM(S): Mus musculus 
2011-03-21 | E-MEXP-2689 | biostudies-arrayexpress
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