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MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
MetabolomicsOrnithine Decarboxylase in Gastric Epithelial Cells Promotes the Immunopathogenesis of Helicobacter pylori Infection

Colonization by H. pylori is associated with a wide range of gastric diseases, ranging from superficial gastritis to more severe pathologies, including intestinal metaplasia and adenocarcinoma. The interplay of the host response and the pathogen affect the outcome of disease. One major component ...

2022-06-15 | MTBLS3235 | MetaboLights
TranscriptomicsExpression profiling of murine hemopoietic cell survival on oligo arrays.
Deregulated cell survival programs are a classical hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta-c subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor that selectively and independently promotes cell survival. We now show that S...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18220 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine hemopoietic cell survival on cDNA arrays.
Deregulated cell survival programs are a classical hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta-c subunit of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor that selectively and independently promotes cell survival. We now show that S...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18221 | biostudies-arrayexpress
UnknownMental health across the early years in the military.
Not available
S-EPMC10277765 | biostudies-literature
Unknown2466. What’s Lurking in the Drain? Serial transmission of NDM-1Klebsiella pneumoniae to patients admitted 9 months apart to the same ICU room
Not available
S-EPMC6809693 | biostudies-literature
TranscriptomicsExpression profiling of murine hemopoietic cell survival
This SuperSeries is composed of the following subset Series: GSE18220: Expression profiling of murine hemopoietic cell survival on oligo arrays. GSE18221: Expression profiling of murine hemopoietic cell survival on cDNA arrays. Refer to individual Series
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-18222 | biostudies-arrayexpress
UnknownAn imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets.
Not available
S-EPMC5433149 | biostudies-literature
UnknownINHALE-1: A Multicenter Randomized Trial of Inhaled Technosphere Insulin in Children With Type 1 Diabetes.
Not available
S-EPMC12818954 | biostudies-literature
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
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