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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownHospitals Participating In ACOs Tend To Be Large And Urban, Allowing Access To Capital And Data.
Not available
S-EPMC4838188 | biostudies-literature
MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
ProteomicsHBPP_MultipleSclerosis_Phos
HBPP_MultipleSclerosis_Phospho
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005154 | PeptideAtlas
ProteomicsHBPP_NormalControl_Phos
HBPP_NormalControl_Phospho
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005150 | PeptideAtlas
ProteomicsUrbanization Project Data Pt 2: Matses, Tunapuco, Guayabo, Tambo, Norman, Burkina Faso. C18 Pos
Second run of the urbanization project -- the core human fecal metabolome. Contains raw and converted data files. Samples were from Matses, Tunapuco, Guayabo, Tambo de Mora, Norman, and Boulkiemdé populations.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-11 | MSV000084794 | MassIVE
UnknownIRF2BPL Is Associated with Neurological Phenotypes.
Not available
S-EPMC6081494 | biostudies-literature
UnknownFamily genetic result communication in rare and undiagnosed disease communities: Understanding the practice.
Not available
S-EPMC8207526 | biostudies-literature
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