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TranscriptomicsRNA-seq of Zbtb20-expressing Tregs against activated (CD62Llo) and naive (CD62Lhi) Tregs that do not express Zbtb20
The objective of this study was to determine if a subset of regulatory T cells (Tregs) expressing the transcription factor, Zbtb20, played a unique role in the function of the immune system. Genetic reporter mice were used to isolate Zbtb20-expressing Tregs as well as activated (CD62Llo) and naive (...
ORGANISM(S): Mus musculus 
2022-02-25 | E-MTAB-11442 | biostudies-arrayexpress
TranscriptomicsHer2/Neu breast cancer mouse model whole tissue transcriptome
Purpose: We generated extensive transcriptional and proteomic profiles from a Her2-driven mouse model of breast cancer that closely recapitulates human breast cancer. This report makes these data publicly available in raw and processed forms, as a resource to the community. Importantly, we previo...
ORGANISM(S): Mus musculus 
2010-10-22 | E-GEOD-20465 | biostudies-arrayexpress
TranscriptomicsHer2/Neu breast cancer mouse model transcriptome
Purpose: We generated extensive transcriptional and proteomic profiles from a Her2-driven mouse model of breast cancer that closely recapitulates human breast cancer. This report makes these data publicly available in raw and processed forms, as a resource to the community. Importantly, we previo...
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-20280 | biostudies-arrayexpress
TranscriptomicsArray comparative genomic hybridization in sporadic and coeliac disease-related small bowel adenocarcinomas
Background: The molecular pathogenesis of small intestinal adenocarcinomas (SBA) is not well understood. Defining its molecular pathogenesis may lead us to better clinical interventions. Aim: to identify the molecular changes characteristic of SBA. Methods: Forty-eight SBA (thirty-three non coelia...
ORGANISM(S): Homo sapiens 
2009-10-07 | E-GEOD-15470 | biostudies-arrayexpress
TranscriptomicsICGC Pancreas: Genomic analysis reveals roles for chromatin modification and axonguidance in pancreatic cancer
Pancreatic cancer (PC) is the fourth leading cause of cancer death with an overall 5-year survival rate of < 5%, a statistic that has changed little in almost 50 years. A deeper understanding of the underlying molecular pathophysiology is expected to advance the urgent need to develop novel therapeu...
ORGANISM(S): Homo sapiens 
2012-03-30 | E-GEOD-36924 | biostudies-arrayexpress
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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